⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7801129 | 0.97 | — | — | |
| SCHEMBL2706065 | 0.82 | — | — | |
| Malonic Acid SCHEMBL28252329 | 0.79 | TSHR (0.77) | — | |
| SCHEMBL28522 | 0.78 | LDHA (0.67) | — | |
| SCHEMBL2184678 | 0.78 | LDHA (0.67) | — | |
| SCHEMBL11345455 | 0.75 | — | — | |
| SCHEMBL320091 | 0.74 | LDHA (0.61) | — | |
| SCHEMBL11603188 | 0.74 | LDHA (0.61) | — | |
| SCHEMBL320485 | 0.74 | LDHA (0.61) | — | |
| SCHEMBL28480654 | 0.74 | LDHA (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073371-B | Preparation method of 4-bromomethylquinolinone | 四川沃肯精细化工有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-112125888-A | Preparation method of 3- (1-methyl-1H-pyrazol-4-yl) -6-quinoxalinamine | 苏州明锐医药科技有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-112125889-A | Preparation method of 7-bromo-2- (1-methyl-1H-pyrazol-4-yl) quinoxaline | 苏州明锐医药科技有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-105585539-B | The method of one pot process cefotaxime side chain acetoacetic ester | 山东金城医药化工有限公司 | 2018-01-23 | — | — | CN | claimed |
| CN-102627596-A | Preparation method of 4-hydroxy-2-oxo-1-pyrrolidine acetamide | TIANJIN JINGYIN PHARMACEUTICAL BIOTECHNOLOGY DEV CO LTD | 2012-08-08 | — | — | CN | claimed |
| EP-1926821-B1 | Method of enantioselective enzymatic reduction of keto compounds | IEP GMBH (DE) | 2011-04-20 | — | — | EP | claimed |
| US-20090324682-A1 | Medical stent provided with inhibitors of atp synthesis | INTERSTITIAL THERAPEUTICS (CH) | 2009-12-31 | — | — | US | claimed |
| EP-1851322-B1 | METHOD FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GMBH (DE) | 2009-10-21 | — | — | EP | claimed |
| EP-1213354-B1 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL CO (JP) | 2007-05-30 | — | — | EP | claimed |
| EP-1789030-A2 | MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS | Interstitial Therapeutics (CH) | 2007-05-30 | — | — | EP | claimed |
| EP-1789107-A2 | MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS | Interstitial Therapeutics (CH) | 2007-05-30 | — | — | EP | claimed |
| WO-2006024488-A2 | MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS | INTERSTITIAL THERAPEUTICS (CH) | 2006-03-09 | — | — | WO | claimed |
| WO-2006024492-A2 | MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS | INTERSTITIAL THERAPEUTICS (CH) | 2006-03-09 | — | — | WO | claimed |
| US-6884607-B2 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-26 | — | — | US | claimed |
| US-20050019816-A1 | Process for producing optically active-4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-01-27 | — | — | US | claimed |
| EP-0967271-B1 | NOVEL CARBONYL REDUCTASE, GENE THAT ENCODES THE SAME, AND METHOD OF UTILIZING THESE | KANEKA CORP (JP) | 2004-10-20 | — | — | EP | claimed |
| US-20030134402-A1 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | claimed |
| EP-1213354-A2 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-12 | — | — | EP | claimed |
| EP-0902016-B1 | A process and intermediate compounds for the preparation of amlodipine benzene sulphonate | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2002-05-02 | — | — | EP | claimed |
| CN-122012607-A | Gene PbTCP for regulating and controlling pear fruit stone cells | 南京农业大学三亚研究院 | 2026-05-12 | — | — | CN | disclosed |
| CN-122012608-A | Gene PbMYB20 for regulating and controlling pear fruit stone cell formation | 南京农业大学三亚研究院 | 2026-05-12 | — | — | CN | disclosed |
| CN-120463988-A | High-barrier PP solid medicinal hard tablet and preparation method thereof | 四川汇利实业有限公司 | 2025-08-12 | — | — | CN | disclosed |
| CN-119592619-A | Gene PbrbHLH195,195 for regulating and controlling lignin synthesis of pear fruit | 南京农业大学三亚研究院 | 2025-03-11 | — | — | CN | disclosed |
| CN-118614539-A | Synergistic treatment method for promoting rapid healing of mechanical injury of sweet potato tuberous root | 四川农业大学 | 2024-09-10 | — | — | CN | disclosed |
| CN-118420527-A | Preparation method of 4-bromomethylquinolinone | 山东洪方精细化工有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-117327710-A | Intercellular continuous filament callose binding protein gene for regulating and controlling pear lignin synthesis | 南京农业大学 | 2024-01-02 | — | — | CN | disclosed |
| CN-117264947-A | Pear CRISPR/Cas9 gene editing system and application thereof | 南京农业大学 | 2023-12-22 | — | — | CN | disclosed |
| US-20230400766-A1 | ONIUM SALT, RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-12-14 | — | — | US | disclosed |
| CN-112390823-B | Synthesis method of minodronic acid | 鲁南制药集团股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-114107366-B | Efficient induction system for pear pulp callus lignin synthesis and application thereof | 南京农业大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-116370632-A | Cold gel for preventing chapped skin by combining photodynamic therapy and preparation method thereof | 杭州惠康医疗器械有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-116199758-A | Pear transcription factor PbrMYB24 and application thereof in promoting synthesis of lignin and cellulose in stone cells | 南京农业大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-115073371-B | Preparation method of 4-bromomethylquinolinone | 四川沃肯精细化工有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-115073371-B | Preparation method of 4-bromomethylquinolinone | 四川沃肯精细化工有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-112390794-B | Preparation method of minodronic acid key intermediate | 鲁南制药集团股份有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-115190901-A | Carbodiimide composition, curing agent composition, coating composition, and resin cured product | 旭化成株式会社 | 2022-10-14 | — | — | CN | disclosed |
| CN-110577960-B | Pear lignin synthesis gene PbMC1a/1b and application thereof in genetic improvement of fruit quality | 南京农业大学 | 2022-09-13 | — | — | CN | disclosed |
| CN-114107366-A | Efficient induction system for synthesizing lignin from pear pulp callus and application | 南京农业大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-112125889-A | Preparation method of 7-bromo-2- (1-methyl-1H-pyrazol-4-yl) quinoxaline | 苏州明锐医药科技有限公司 | 2020-12-25 | — | — | CN | disclosed |
| CN-112125888-A | Preparation method of 3- (1-methyl-1H-pyrazol-4-yl) -6-quinoxalinamine | 苏州明锐医药科技有限公司 | 2020-12-25 | — | — | CN | disclosed |
| CN-111139253-B | Cryptomeria fortunei CfCCR gene and application thereof | 南京林业大学 | 2020-12-22 | — | — | CN | disclosed |
| CN-111139253-A | Cryptomeria fortunei CfCCR gene and application thereof | 南京林业大学 | 2020-05-12 | — | — | CN | disclosed |
| CN-110577960-A | pear lignin synthesis gene PbMC1a/1b and application thereof in genetic improvement of fruit quality | 南京农业大学 | 2019-12-17 | — | — | CN | disclosed |
| US-10241116-B2 | Dual-sensitizer-containing luminescent compounds, conjugates, and uses thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-03-26 | — | — | US | disclosed |
| US-20170016907-A1 | DUAL-SENSITIZER-CONTAINING LUMINESCENT COMPOUNDS, CONJUGATES, AND USES THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-01-19 | — | — | US | disclosed |
| CN-104744399-B | A kind of preparation method of cefcapene side-chain acid | 浙江华方药业股份有限公司 | 2016-09-14 | — | — | CN | disclosed |
| US-9415111-B2 | Dual-sensitizer-containing luminescent compounds, conjugates, and uses thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-08-16 | — | — | US | disclosed |
| CN-105585539-A | One-pot ceftazidime side-chain acid ethyl ester synthesis method | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL CO LTD | 2016-05-18 | — | — | CN | disclosed |
| CN-103351322-B | A kind of synthetic method of oxiracetam | GUANG'AN KINGDAY PHARM & CHEMICAL CO., LTD. (CN) | 2015-11-25 | — | — | CN | disclosed |
| EP-2348865-B1 | BETA-HYDROXY-GAMMA-AMINOPHOSPHONATES AND METHODS FOR THE PREPARATION AND USE THEREOF | NUCITEC SA DE CV (MX) | 2015-07-15 | — | — | EP | disclosed |
| US-8536362-B2 | β-hydroxy-γ-aminophosphonates and methods for the preparation and use thereof | NUCITEC S.A. DE C.V. (MX) | 2013-09-17 | — | — | US | disclosed |
| US-20130079308-A1 | Beta-Hydroxy-Gamma-Aminophosphonates and Methods for the Preparation and Use Thereof | NUCITEC S.A. DE C.V. (MX) | 2013-03-28 | — | — | US | disclosed |
| CN-102627596-A | Preparation method of 4-hydroxy-2-oxo-1-pyrrolidine acetamide | TIANJIN JINGYIN PHARMACEUTICAL BIOTECHNOLOGY DEV CO LTD | 2012-08-08 | — | — | CN | disclosed |
| US-8178515-B2 | β-hydroxy-γ-aminophosphonates and methods for the preparation and use thereof | NUCITEC S.A. DE C.V. (MX) | 2012-05-15 | — | — | US | disclosed |
| EP-2348865-A2 | BETA-HYDROXY-GAMMA-AMINOPHOSPHONATES AND METHODS FOR THE PREPARATION AND USE THEREOF | Nucitec S.A. de C.V. (MX) | 2011-08-03 | — | — | EP | disclosed |
| US-20110124704-A1 | DEUTERIUM-ENRICHED ATORVASTATIN | PROTIA, LLC (US) | 2011-05-26 | — | — | US | disclosed |
| US-20100178251-A1 | Dual-Sensitizer-Containing Luminescent Compounds, Conjugates, and Uses Thereof | THE UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2010-07-15 | — | — | US | disclosed |
| US-7745480-B2 | Deuterium-enriched atorvastatin | PROTIA, LLC (US) | 2010-06-29 | — | — | US | disclosed |
| WO-2010041144-A2 | BETA-HYDROXY-GAMMA-AMINOPHOSPHONATES AND METHODS FOR THE PREPARATION AND USE THEREOF | NUCITEC S.A. DE C.V. (MX) | 2010-04-15 | — | — | WO | disclosed |
| US-20100087400-A1 | Beta-Hydroxy-Gamma-Aminophosphonates and Methods for the Preparation and Use Thereof | NUCITEC S.A. DE C.V. (MX) | 2010-04-08 | — | — | US | disclosed |
| US-20090324682-A1 | Medical stent provided with inhibitors of atp synthesis | INTERSTITIAL THERAPEUTICS (CH) | 2009-12-31 | — | — | US | disclosed |
| WO-2009154785-A2 | C4-SUBSTITUTED ALPHA-KETO OXAZOLES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-12-23 | — | — | WO | disclosed |
| EP-2056709-A1 | DUAL-SENSITIZER-CONTAINING LUMINESCENT COMPOUNDS, CONJUGATES, AND USES THEREOF | The University of Medicine and Dentistry of New Jersey (US) | 2009-05-13 | — | — | EP | disclosed |
| US-20080280970-A1 | DEUTERIUM-ENRICHED ATORVASTATIN | PROTIA, LLC | 2008-11-13 | — | — | US | disclosed |
| US-20080280971-A1 | deuterated (3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid, used for the treatment of dyslipidemia and/or hyperlipemia | PROTIA, LLC (US) | 2008-11-13 | — | — | US | disclosed |
| US-20080242716-A1 | calcium channel modulator; [1-(4-Chloro-phenyl)-2-(4-fluoro-benzyl)-1H-imidazol-4-ylmethyl]-(4-fluoro-phenyl)-)-methyl-amine; analgesic, antidiabetic agent; angina, hypertension, myocardial ischemia, arrhythmia, diabetes, urinary incontinence, stroke, pain, brain injury, or neuronal disorders | SCION PHARMACEUTICALS, INC. | 2008-10-02 | — | — | US | disclosed |
| EP-1378566-B1 | Modified reductase from Penicillium citrinum and its encoding gene | SUMITOMO CHEMICAL CO (JP) | 2008-08-06 | — | — | EP | disclosed |
| WO-2008019403-A1 | DUAL-SENSITIZER-CONTAINING LUMINESCENT COMPOUNDS, CONJUGATES, AND USES THEREOF | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2008-02-14 | — | — | WO | disclosed |
| US-20070292478-A1 | Medical Implant Provided with Inhibitors of Atp Synthesis | INTERSTITIAL THERAPEUTICS (CH) | 2007-12-20 | — | — | US | disclosed |
| US-20070281937-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2007-12-06 | — | — | US | disclosed |
| EP-1722787-A4 | ION CHANNEL MODULATORS | WYETH CORP (US) | 2007-09-26 | — | — | EP | disclosed |
| EP-1723120-A4 | ION CHANNEL MODULATORS | WYETH CORP (US) | 2007-09-26 | — | — | EP | disclosed |
| US-20070197513-A1 | Ion channel modulators | SCION PHARMACEUTICALS, INC. | 2007-08-23 | — | — | US | disclosed |
| US-20070197619-A1 | Ion Channel Modulators | WYETH | 2007-08-23 | — | — | US | disclosed |
| EP-1213354-B1 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL CO (JP) | 2007-05-30 | — | — | EP | disclosed |
| EP-1789030-A2 | MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS | Interstitial Therapeutics (CH) | 2007-05-30 | — | — | EP | disclosed |
| EP-1789107-A2 | MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS | Interstitial Therapeutics (CH) | 2007-05-30 | — | — | EP | disclosed |
| CN-1938022-A | Ion channel modulators | SCION PHARMACEUTICALS INC (US) | 2007-03-28 | — | — | CN | disclosed |
| EP-1386961-B1 | Modified reductase and its gene and use thereof | SUMITOMO CHEMICAL CO (JP) | 2007-03-21 | — | — | EP | disclosed |
| EP-1722787-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2006-11-22 | — | — | EP | disclosed |
| EP-1723120-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2006-11-22 | — | — | EP | disclosed |
| EP-1723119-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2006-11-22 | — | — | EP | disclosed |
| EP-1723117-A2 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2006-11-22 | — | — | EP | disclosed |
| WO-2006024488-A2 | MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS | INTERSTITIAL THERAPEUTICS (CH) | 2006-03-09 | — | — | WO | disclosed |
| WO-2006024492-A2 | MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS | INTERSTITIAL THERAPEUTICS (CH) | 2006-03-09 | — | — | WO | disclosed |
| WO-2005087229-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005087747-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005087748-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005086836-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2005-09-22 | — | — | WO | disclosed |
| US-6884607-B2 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-26 | — | — | US | disclosed |
| US-6884607-B2 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-26 | — | — | US | disclosed |
| US-20050019816-A1 | Process for producing optically active-4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-01-27 | — | — | US | disclosed |
| US-20050019816-A1 | Process for producing optically active-4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-01-27 | — | — | US | disclosed |
| US-20030134402-A1 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | disclosed |
| US-20030134402-A1 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | disclosed |
| EP-0999202-B1 | Process for producing 2-alkylidene-4-bromoacetoacetic acid ester | SUMITOMO CHEMICAL CO (JP) | 2003-03-19 | — | — | EP | disclosed |
| WO-2003020709-A1 | 1,2-OXAZIN-3-ONE DERIVATIVES AS ANTIBACTERIAL AGENTS | SIMON FRASER UNIVERSITY (CA) | 2003-03-13 | — | — | WO | disclosed |
| EP-1213354-A3 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-02-05 | — | — | EP | disclosed |
| CN-1382140-A | Neurotrophic pyrrolidines and piperidines and related compositions containing them | ORTHO MCNEIL PHARM INC (US) | 2002-11-27 | — | — | CN | disclosed |
| US-6469200-B1 | A PROCESS WHICH CAN PROVIDE THE DESIRED 2-ALKYLIDENE-4-BROMOACETOACETIC ACID ESTER BY USING, AS A STARTING MATERIAL, A 4-BROMOACETOACETIC ACID ESTER WHICH CAN BE READILY DERIVED FROM AN ACETOACETIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| JP-2002233392-A | METHOD FOR PRODUCING OPTICALLY ACTIVE 4-BROMO-3- HYDROXYBUTANOATE | SUMITOMO CHEM CO LTD | 2002-08-20 | — | — | JP | disclosed |
| CN-1086704-C | Compound having antihypertensive, cardioprotective, anti-ischemic and antilipolytic functions | AVENTIS PHARMA INC (US) | 2002-06-26 | — | — | CN | disclosed |
| EP-1213354-A2 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-12 | — | — | EP | disclosed |
| EP-1213354-A2 | Process for producing optically active 4-halo-3-hydroxybutanoate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-12 | — | — | EP | disclosed |
| EP-0999202-A1 | Process for producing 2-alkylidene-4-bromoacetoacetic acid ester | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-5856320-A | ANTIBIOTIC RESISTANT STAPYLOCOCCUS | KATAYAMA SEIYAKUSYO CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0771803-A1 | Pyrazolo(1,5-a)pyrimidinium substituted cephem derivatives, their preparation and their use as antimicrobial agents | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |
| EP-0402246-B1 | Thiazolylalkoxyacrylates, process for their preparation, their use as fungicides and intermediates in their preparation | ROUSSEL UCLAF (FR) | 1994-08-24 | — | — | EP | disclosed |
| EP-0573184-A1 | t-Butyl (R)-(-)-4-Cyano-3-hydroxybutyrate and process for its preparation | Takasago International Corporation (JP) | 1993-12-08 | — | — | EP | disclosed |
| EP-0339764-B1 | PROCESS FOR PREPARING CARNITINE | Takasago International Corporation (JP) | 1992-06-24 | — | — | EP | disclosed |
| US-5079369-A | N-acylating agent | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0402246-A1 | Thiazolylalkoxyacrylates, process for their preparation, their use as fungicides and intermediates in their preparation | ROUSSEL-UCLAF (FR) | 1990-12-12 | — | — | EP | disclosed |
| EP-0339764-A1 | Process for preparing carnitine | Takasago International Corporation (JP) | 1989-11-02 | — | — | EP | disclosed |
| US-4877873-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| US-4871860-A | Syn-isomer of 3,7-disubstituted-3-cephem-4-caroxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |
| US-4804752-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-14 | — | — | US | disclosed |
| EP-0169614-B1 | PROCESS FOR THE PREPARATION OF L-CARNITINE | SCLAVO S.p.A. (IT) | 1988-11-30 | — | — | EP | disclosed |
| EP-0102893-B1 | A NOVEL PRODUCTION OF 1-OXACEPHAMS | SHIONOGI & CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |
| US-4642290-A | OXIDOREDUCTASE ENZYMES FERMENTING 4-SUBSTITUTED-ACETOACETIC ESTERS OR AMIDES | SIH CHARLES J (US) | 1987-02-10 | — | — | US | disclosed |
| EP-0169614-A2 | Process for the preparation of L-carnitine | SCLAVO S.p.A. (IT) | 1986-01-29 | — | — | EP | disclosed |
| EP-0160876-A1 | 1-Hetero-6-/1-Hydroxyethyl/-2-SR8-1-carbadethiapen-2-EM-3-carboxylic acids | MERCK & CO. INC. (US) | 1985-11-13 | — | — | EP | disclosed |
| US-4544653-A | BACTERICIDAL CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-01 | — | — | US | disclosed |
| US-4539148-A | OXYGENATED BUTYRIC ACID DERIVATIVES OF OXOAZETIDINE | SHIONOGI & CO., LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| US-4493833-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| EP-0102893-A1 | A novel production of 1-oxacephams | SHIONOGI & CO., LTD. (JP) | 1984-03-14 | — | — | EP | disclosed |
| US-4431643-A | CEPHALOSPORINS; BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-02-14 | — | — | US | disclosed |
| US-4364943-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-12-21 | — | — | US | disclosed |
| US-4331664-A | BACTERIOSTATS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-05-25 | — | — | US | disclosed |
| US-4316019-A | AMIDATION BY A 2-ALKOXYIMINO-2-THIAZOLYLACETIC ACID | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-02-16 | — | — | US | disclosed |
| US-4304770-A | Syn-isomer of 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4279818-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-21 | — | — | US | disclosed |
| US-4166115-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4033978-A | Thiacycl[2.2.2]azine carboxylic acids | SYNTEX (U.S.A.) INC. (US) | 1977-07-05 | — | — | US | disclosed |
| US-4021480-A | Process for the production of carnitine | LONZA LTD. (CH) | 1977-05-03 | — | — | US | disclosed |
| US-4018821-A | Process for the production of carnitine | LONZA LTD. (CH) | 1977-04-19 | — | — | US | disclosed |
| US-3965168-A | CITRIC ACID INTERMEDIATE | ETHYL CORPORATION (US) | 1976-06-22 | — | — | US | disclosed |
| US-3960941-A | CHEMICAL INTERMEDIATE FOR CITRIC ACID | ETHYL CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
| US-3950412-A | Method for the production of haloacetoacetic acids | LONZA LTD. (CH) | 1976-04-13 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |