Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.61 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.61 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KDM6B | O15054 | 2/20 | 0.36 |
| ▸ | KDM5C | P41229 | 2/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320485 | 1.00 | LDHA (0.61) | LDHASRREGLN1LMNAALKBH5 | |
| SCHEMBL2184678 | 0.96 | LDHA (0.67) | LDHASRREGLN1LMNAALKBH5 | |
| SCHEMBL28522 | 0.96 | LDHA (0.67) | LDHASRREGLN1LMNAALKBH5 | |
| SCHEMBL15422862 | 0.92 | LDHA (0.61) | LDHASRREGLN1LMNAALKBH5 | |
| SCHEMBL28480654 | 0.92 | LDHA (0.61) | LDHASRREGLN1LMNAALKBH5 | |
| SCHEMBL11603188 | 0.92 | LDHA (0.61) | LDHASRREGLN1LMNAALKBH5 | |
| Hydrazine SCHEMBL28819948 | 0.88 | LDHA (0.57) | LDHASRREGLN1LMNAALKBH5 | |
| SCHEMBL7785189 | 0.84 | LDHA (0.44) | LDHASRREGLN1LMNAALKBH5 | |
| SCHEMBL1142940 | 0.84 | TDP1 (0.50) | LDHASRREGLN1TSHRFFAR3 | |
| SCHEMBL18342669 | 0.84 | PHF8 (0.59) | LDHASRREGLN1LMNAALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183391-A1 | Biosynthesis of Phloroglucinol and Preparation of 1,3-Dihydroxybenzene Therefrom | BOARD OF TRUSTEES OF MICHIGAN STATE OF UNIVERSITY (US) | 2011-07-28 | — | — | US | disclosed |
| US-7943362-B2 | Biosynthesis of phloroglucinol and preparation of 1,3-dihydroxybenzene therefrom | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2011-05-17 | — | — | US | disclosed |