Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30172471 | 0.84 | TSHR (0.58) | PTPN1TSHRALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL28431632 | 0.79 | TSHR (0.52) | PTPN1TSHRALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL23149896 | 0.76 | NR1H3 (0.50) | PTPN1TSHRALDH1A1CYP1A2NR1H2 | |
| SCHEMBL23149882 | 0.75 | PTPN1 (0.48) | PTPN1TSHRALDH1A1CYP1A2NR1H2 | |
| SCHEMBL13219505 | 0.74 | ALDH1A1 (0.52) | PTPN1TSHRALDH1A1CYP1A2NR1H2 | |
| SCHEMBL7967046 | 0.74 | TSHR (0.52) | PTPN1TSHRALDH1A1CYP1A2NR1H2 | |
| SCHEMBL5865852 | 0.74 | TSHR (0.52) | PTPN1TSHRALDH1A1CYP1A2NR1H2 | |
| SCHEMBL8321565 | 0.74 | TSHR (0.52) | PTPN1TSHRALDH1A1CYP1A2NR1H2 | |
| SCHEMBL2864482 | 0.74 | NR1H3 (0.57) | PTPN1TSHRALDH1A1NR1H2NR1H3 | |
| SCHEMBL10601697 | 0.74 | TSHR (0.52) | PTPN1TSHRALDH1A1CYP1A2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856732-B2 | Tracers | RESTRACK AS (NO) | 2018-01-02 | — | — | US | disclosed |
| EP-2935508-B1 | TRACERS | RESTRACK AS (NO) | 2017-02-15 | — | — | EP | disclosed |
| US-20160003040-A1 | Tracers | Resman Technology AS (NO) | 2016-01-07 | — | — | US | disclosed |
| EP-2935508-A1 | TRACERS | Restrack AS (NO) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014096459-A1 | TRACERS | RESTRACK AS (NO) | 2014-06-26 | — | — | WO | disclosed |