Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13736869 | 0.89 | RORC (0.55) | TSHRALDH1A1NR1H2NR1I2RORC | |
| SCHEMBL5865830 | 0.87 | NR1H2 (0.51) | TSHRALDH1A1NR1H2NR1I2RORC | |
| SCHEMBL25985492 | 0.87 | NR1H2 (0.47) | TSHRALDH1A1NR1H2NR1I2PTPN1 | |
| SCHEMBL11608877 | 0.87 | ALDH1A1 (0.46) | TSHRALDH1A1NR1H2NR1I2PTPN1 | |
| SCHEMBL1815767 | 0.87 | NR1H2 (0.47) | TSHRALDH1A1NR1H2NR1I2PTPN1 | |
| Hydrochloric Acid SCHEMBL18275180 | 0.85 | NR1H2 (0.46) | TSHRALDH1A1NR1H2NR1I2PTPN1 | |
| SCHEMBL2228773 | 0.84 | TSHR (0.48) | TSHRALDH1A1NR1H2NR1I2PTPN1 | |
| SCHEMBL15497439 | 0.83 | TSHR (0.48) | TSHRALDH1A1NR1H2NR1I2RORC | |
| SCHEMBL18275136 | 0.83 | SRD5A2 (0.53) | TSHRNR1H2NR1I2PTPN1NR1H3 | |
| SCHEMBL7173455 | 0.82 | CYP1A2 (0.48) | TSHRALDH1A1PTPN1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110776404-B | Method for rhenium ionic liquid assisted multi-stage pore metal organic framework material catalytic alcohol oxidation to aldehyde | 辽宁大学 | 2022-06-14 | — | — | CN | claimed |
| CN-110776404-A | Method for rhenium ionic liquid assisted multi-stage pore metal organic framework material catalytic alcohol oxidation to aldehyde | 辽宁大学 | 2020-02-11 | — | — | CN | claimed |
| US-9334253-B2 | Direct trifluoromethylations using trifluoromethane | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2016-05-10 | — | — | US | claimed |
| US-20140066640-A1 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2014-03-06 | — | — | US | claimed |
| US-7087789-B2 | Methods for nucleophilic fluoromethylation | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2006-08-08 | — | — | US | claimed |
| US-20040230079-A1 | Methods for nucleophilic fluoromethylation | SOUTHERN CALIFORNIA, UNIVERSITY OF | 2004-11-18 | — | — | US | claimed |
| WO-2004063129-A2 | METHODS FOR NUCLEOPHILIC FLUOROMETHYLATION | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2004-07-29 | — | — | WO | claimed |
| CN-110776404-B | Method for rhenium ionic liquid assisted multi-stage pore metal organic framework material catalytic alcohol oxidation to aldehyde | 辽宁大学 | 2022-06-14 | — | — | CN | disclosed |
| US-20210032184-A1 | RADIOLABELING AGENTS, METHODS OF MAKING, AND METHODS OF USE THEREOF | THE US SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) | 2021-02-04 | — | — | US | disclosed |
| CN-110776404-A | Method for rhenium ionic liquid assisted multi-stage pore metal organic framework material catalytic alcohol oxidation to aldehyde | 辽宁大学 | 2020-02-11 | — | — | CN | disclosed |
| US-10450253-B2 | Preparation process of perfluoroalkyl compound with monohydroperfluoroalkane as starting material | KANTO DENKA KOGYO CO., LTD. (JP) | 2019-10-22 | — | — | US | disclosed |
| US-20190270689-A1 | Radiolabeling Agents, Methods of Making, and Methods of Use Thereof | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2019-09-05 | — | — | US | disclosed |
| EP-3495341-A1 | METHOD FOR PRODUCING PERFLUOROALKYL COMPOUND USING MONOHYDROPERFLUOROALKANE AS STARTING MATERIAL | Kanto Denka Kogyo Co., Ltd. (JP) | 2019-06-12 | — | — | EP | disclosed |
| EP-0946504-B1 | COMPOUNDS USEFUL FOR PERHALOGENOALKYLATION, REAGENT FOR IMPLEMENTING THESE COMPOUNDS AND SYNTHESIS METHOD FOR OBTAINING THESE COMPOUNDS | RHODIA CHIMIE SA (FR) | 2003-08-13 | — | — | EP | disclosed |
| EP-1096926-A2 | METHODS AND COMPOUNDS FOR TREATING DEPRESSION | NPS PHARMACEUTICALS, INC. (US) | 2001-05-09 | — | — | EP | disclosed |
| US-6203721-B1 | FOR GRAFTING A SUBSTITUTED DIFLUOROMETHYL GROUP ONTO A COMPOUND CONTAINING ELECTROPHILIC GROUP | RHODIA CHIMIE (FR) | 2001-03-20 | — | — | US | disclosed |
| WO-2000002551-A2 | METHODS AND COMPOUNDS FOR TREATING DEPRESSION | NPS PHARMACEUTICALS, INC. (US) | 2000-01-20 | — | — | WO | disclosed |
| EP-0946504-A1 | COMPOUNDS USEFUL FOR PERHALOGENOALKYLATION, REAGENT FOR IMPLEMENTING THESE COMPOUNDS AND SYNTHESIS METHOD FOR OBTAINING THESE COMPOUNDS | RHODIA CHIMIE (FR) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998022435-A9 | COMPOUNDS USEFUL FOR PERHALOGENOALKYLATION, REAGENT FOR IMPLEMENTING THESE COMPOUNDS AND SYNTHESIS METHOD FOR OBTAINING THESE COMPOUNDS | RHODIA CHIMIE SA (FR) | 1999-08-26 | — | — | WO | disclosed |
| WO-1998022435-A1 | COMPOUNDS USEFUL FOR PERHALOGENOALKYLATION, REAGENT FOR IMPLEMENTING THESE COMPOUNDS AND SYNTHESIS METHOD FOR OBTAINING THESE COMPOUNDS | RHODIA CHIMIE (FR) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040230079-A1 | Methods for nucleophilic fluoromethylation | PHF2, HAO2, GSTM2 | TSHR 2421/4885ALDH1A1 1240/4885NR1H2 3340/4885 |
| US-20190270689-A1 | Radiolabeling Agents, Methods of Making, and Methods of Use Thereof | PFAS, TMEM14C, FLI1 | TSHR 547/4885ALDH1A1 2055/4885NR1H2 1559/4885 |
| US-20140066640-A1 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE | TST, FLI1, CYP2F1 | TSHR 2475/4885ALDH1A1 1358/4885NR1H2 3490/4885 |
| US-20210032184-A1 | RADIOLABELING AGENTS, METHODS OF MAKING, AND METHODS OF USE THEREOF | TMEM14C, PFAS, FLI1 | TSHR 522/4885ALDH1A1 2039/4885NR1H2 1499/4885 |
| US-10450253-B2 | Preparation process of perfluoroalkyl compound with monohydroperfluoroalkane as starting material | PFKFB1, PFKFB4, PFAS | TSHR 2116/4885ALDH1A1 505/4885NR1H2 463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.