SCHEMBL15822263

SCHEMBL15822263

C=C(C(=O)O)C(CC)n1c2ccccc2c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.49
KDM4E B2RXH2 6/20 0.41
ALDH1A1 P00352 4/20 0.40
KMT2A Q03164 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
FABP4 P15090 3/20 0.39
FABP5 Q01469 3/20 0.39
FABP3 P05413 1/20 0.39
TSPO P30536 2/20 0.39
HPGD P15428 3/20 0.38
MEN1 O00255 1/20 0.37
HSD17B10 Q99714 1/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7149835 0.83 POLB (0.64) POLBKDM4EALDH1A1KMT2AL3MBTL1
SCHEMBL27830151 0.79 POLB (0.49) POLBKDM4EALDH1A1FABP4FABP5
SCHEMBL13682967 0.70 FNTA (0.55) POLBKDM4EALDH1A1KMT2AL3MBTL1
SCHEMBL2678031 0.70 BACE1 (0.56) KDM4EALDH1A1KMT2AFABP4FABP5
SCHEMBL27841868 0.70 POLB (0.41) POLBKDM4EALDH1A1TSPOHPGD
SCHEMBL14438995 0.70 POLB (0.47) POLB
SCHEMBL9432792 0.69 POLB (0.62) POLBKDM4EALDH1A1HPGDCYP1A2
SCHEMBL11788366 0.69 BACE1 (0.48) POLBKDM4EALDH1A1TSPOCYP1A2
SCHEMBL18890927 0.69 GPR3 (0.43) POLBKDM4EALDH1A1KMT2AL3MBTL1
SCHEMBL573153 0.68 CYP1A2 (0.50) POLBKDM4EALDH1A1KMT2ATSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3997163-B1 FILLER FOR 3D PRINTING QUARZWERKE GMBH (DE) 2023-09-06 EP disclosed
US-10759934-B2 Thermotropic polymers QUARZWERKE GMBH (DE) 2020-09-01 US disclosed
EP-2935509-B1 THERMOTROPIC POLYMERS QUARZWERKE GMBH (DE) 2019-05-22 EP disclosed
US-20150329715-A1 THERMOTROPIC POLYMERS QUARZWERKE GMBH (DE) 2015-11-19 US disclosed
EP-2935509-A2 THERMOTROPIC POLYMERS Quarzwerke GmbH (DE) 2015-10-28 EP disclosed
WO-2014096222-A2 THERMOTROPIC POLYMERS QUARZWERKE GMBH (DE) 2014-06-26 WO disclosed