Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982598 | 0.88 | TERT (0.49) | ALDH1A1GAATERTSMN1; SMN2LMNA | |
| SCHEMBL31397607 | 0.86 | TERT (0.48) | ALDH1A1GAASLC22A2SLC22A1SLC22A3 | |
| SCHEMBL1323372 | 0.82 | CHAT (0.47) | ALDH1A1GAASLC22A2SLC22A1SLC22A3 | |
| SCHEMBL2185887 | 0.81 | USP2 (0.47) | ALDH1A1GAAPSIP1TERTLMNA | |
| SCHEMBL29889955 | 0.81 | USP2 (0.47) | ALDH1A1GAAPSIP1TERTLMNA | |
| Water SCHEMBL25192063 | 0.81 | CHAT (0.46) | ALDH1A1GAASLC22A2SLC22A1SLC22A3 | |
| SCHEMBL142175 | 0.81 | CA12 (0.46) | ALDH1A1GAASLC22A2SLC22A1SLC22A3 | |
| SCHEMBL20583771 | 0.79 | HTR6 (0.55) | ALDH1A1HTR6PSIP1SMN1; SMN2LMNA | |
| Lithium Ion SCHEMBL1457873 | 0.79 | HTR6 (0.55) | ALDH1A1HTR6PSIP1SMN1; SMN2LMNA | |
| SCHEMBL20533805 | 0.79 | HTR6 (0.55) | ALDH1A1HTR6PSIP1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934472-A2 | GENTLE OXIDATIVE HAIR TREATMENT WITH SILICONE PRE-TREATMENT AND BLEACHING FORCE INTENSIFIER | Henkel AG & Co. KGaA (DE) | 2015-10-28 | — | — | EP | claimed |
| WO-2014095179-A2 | GENTLE OXIDATIVE HAIR TREATMENT WITH SILICONE PRE-TREATMENT AND BLEACHING FORCE INTENSIFIER | HENKEL AG & CO. KGAA (DE) | 2014-06-26 | — | — | WO | claimed |