SCHEMBL15823830

SCHEMBL15823830

Cc1cc(C)c(C(=O)P(=O)(O)C(=O)c2c(C)cc(C)cc2C)c(C)c1.[NaH]

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 4/20 0.41
TAS1R1 Q7RTX1 4/20 0.41
TAS1R2 Q8TE23 4/20 0.41
KMT2A Q03164 3/20 0.40
HPGD P15428 2/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PGK1 P00558 2/20 0.38
PGK2 P07205 2/20 0.38
SRC P12931 1/20 0.36
KDM4E B2RXH2 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
ALDH1A1 P00352 2/20 0.35
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15822585 0.98 TAS1R3 (0.42) TAS1R3TAS1R1TAS1R2KMT2AHPGD
Hydrochloric Acid SCHEMBL15823754 0.96 TAS1R3 (0.41) TAS1R3TAS1R1TAS1R2KMT2AHPGD
SCHEMBL21349626 0.88 KMT2A (0.39) TAS1R3TAS1R1TAS1R2KMT2AHPGD
SCHEMBL29131289 0.88 TAS1R3 (0.39) TAS1R3TAS1R1TAS1R2KMT2AHPGD
SCHEMBL28643929 0.87 TAS1R3 (0.41) TAS1R3TAS1R1TAS1R2KMT2AHPGD
SCHEMBL19221711 0.87 TAS1R3 (0.36) TAS1R3TAS1R1TAS1R2KMT2AHPGD
SCHEMBL28106244 0.84 TAS1R3 (0.42) TAS1R3TAS1R1TAS1R2KMT2AHPGD
SCHEMBL21352438 0.84 HPGD (0.36) TAS1R3TAS1R1TAS1R2KMT2AHPGD
SCHEMBL11123471 0.83 TAS1R3 (0.41) TAS1R3TAS1R1TAS1R2KMT2AHPGD
SCHEMBL28701742 0.83 TAS1R3 (0.41) TAS1R3TAS1R1TAS1R2KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935289-B1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM GROUP B V (NL) 2019-06-26 EP disclosed
WO-2019113085-A1 ELECTROCHEMICAL DETECTION SYSTEMS AND COMPONENTS THEREOF Laxmi Therapeutic Devices, Inc. (US) 2019-06-13 WO disclosed
US-20190170739-A1 ELECTROCHEMICAL DETECTION SYSTEMS AND COMPONENTS THEREOF Laxmi Therapeutic Devices, Inc. 2019-06-06 US disclosed
EP-3459957-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM Group B.V. (NL) 2019-03-27 EP disclosed
US-10040810-B2 Derivatives of bisacylphosphinic acid, their preparation and use as photoinitiators BASF SE (DE) 2018-08-07 US disclosed
US-20160039851-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM GROUP B.V. (NL) 2016-02-11 US disclosed
EP-2935289-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS BASF SE (DE) 2015-10-28 EP disclosed
WO-2014095724-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS BASF SE (DE) 2014-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160039851-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS ARSA, ACSL6, RER1 TAS1R3 763/4885TAS1R1 588/4885TAS1R2 825/4885
US-10040810-B2 Derivatives of bisacylphosphinic acid, their preparation and use as photoinitiators ARSA, RER1, ACSL6 TAS1R3 778/4885TAS1R1 579/4885TAS1R2 909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.