Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1582865 | 0.88 | HTR2A (0.51) | HTR2AHTR2CHTR7HTR6CYP2D6 | |
| SCHEMBL1582488 | 0.88 | HTR2A (0.51) | HTR2AHTR2CHTR7HTR6CYP2D6 | |
| SCHEMBL1582906 | 0.87 | HSD11B1 (0.61) | HTR2AHTR2CCYP2C19SMN1; SMN2LMNA | |
| SCHEMBL1582339 | 0.87 | MGLL (0.56) | HTR2AHTR2CHTR7HTR6CYP2D6 | |
| SCHEMBL12722481 | 0.87 | HTR2A (0.56) | HTR2AHTR2CHTR7HTR6CYP2D6 | |
| SCHEMBL1582825 | 0.87 | HTR2A (0.44) | HTR2AHTR2CHTR7HTR6CYP2C19 | |
| SCHEMBL12721483 | 0.86 | HTR2A (0.55) | HTR2AHTR2CHTR7HTR6CYP2D6 | |
| SCHEMBL1583020 | 0.86 | HTR2A (0.55) | HTR2AHTR2CHTR7HTR6CYP2D6 | |
| SCHEMBL1582370 | 0.86 | HTR2A (0.55) | HTR2AHTR2CHTR7HTR6CYP2D6 | |
| SCHEMBL1582730 | 0.85 | HSD11B1 (0.57) | HTR2AHTR2CHTR7HTR6CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546100-B1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK HOLDINGS CO LTD (KR) | 2011-04-20 | — | — | EP | disclosed |
| EP-1546100-B1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK HOLDINGS CO LTD (KR) | 2011-04-20 | — | — | EP | disclosed |
| US-6770659-B2 | Benzoyl piperidine compounds | SK CORPORATION (KR) | 2004-08-03 | — | — | US | disclosed |
| US-20040044033-A1 | New benzoyl piperidine compounds | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044033-A1 | New benzoyl piperidine compounds | GABRE, GRIN2C, GRIN1 | HTR2A 171/4885HTR2C 145/4885HTR7 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.