Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.70 |
| ▸ | CTSS | P25774 | 13/20 | 0.67 |
| ▸ | CTSB | P07858 | 10/20 | 0.67 |
| ▸ | CTSK | P43235 | 9/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273044 | 0.83 | CTSS (0.62) | CTSLCTSSCTSBCTSK | |
| SCHEMBL1199239 | 0.82 | CTSL (0.74) | CTSLCTSSCTSBCTSK | |
| SCHEMBL1199241 | 0.82 | CTSL (0.74) | CTSLCTSSCTSBCTSK | |
| SCHEMBL14324339 | 0.82 | CTSS (0.88) | CTSLCTSSCTSBCTSK | |
| SCHEMBL1272500 | 0.82 | CTSS (0.88) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2133515 | 0.82 | CTSL (0.83) | CTSLCTSSCTSBCTSK | |
| SCHEMBL2156876 | 0.82 | CTSL (0.79) | CTSLCTSSCTSBCTSK | |
| SCHEMBL4412302 | 0.82 | CTSL (0.73) | CTSLCTSSCTSBCTSK | |
| SCHEMBL1271598 | 0.82 | CTSS (0.85) | CTSLCTSSCTSBCTSK | |
| SCHEMBL1200274 | 0.81 | CTSL (0.72) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866277-B1 | SULFONYL CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS | VIROBAY INC (US) | 2014-06-25 | — | — | EP | disclosed |