Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 2/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenbutyramide SCHEMBL1477997 | 0.84 | EPHX1 (0.63) | LMNAHSD17B10EPHX1GAARECQL | |
| Fenbutyramide SCHEMBL1478462 | 0.84 | EPHX1 (0.63) | LMNAHSD17B10EPHX1GAARECQL | |
| Fenbutyramide SCHEMBL232920 | 0.84 | EPHX1 (0.63) | LMNAHSD17B10EPHX1GAARECQL | |
| SCHEMBL710418 | 0.84 | LMNA (0.56) | LMNAHSD17B10GAAALDH1A1POLB | |
| Fenbutyramide SCHEMBL15995561 | 0.82 | EPHX1 (0.61) | LMNAHSD17B10EPHX1GAARECQL | |
| SCHEMBL10591287 | 0.81 | LMNA (0.50) | LMNAHSD17B10EPHX1GAARECQL | |
| SCHEMBL6209773 | 0.81 | LMNA (0.50) | LMNAHSD17B10EPHX1GAARECQL | |
| SCHEMBL4935067 | 0.81 | LMNA (0.61) | LMNAHSD17B10GAAALDH1A1POLB | |
| SCHEMBL16820449 | 0.80 | LMNA (0.56) | LMNAHSD17B10GAATDP1ALDH1A1 | |
| SCHEMBL6410341 | 0.80 | LMNA (0.56) | LMNAHSD17B10GAATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115083-B2 | Compounds from Antrodia cinnamomea and use thereof | SIMPSON BIOTECH CO., LTD. (TW) | 2015-08-25 | — | — | US | disclosed |
| US-20140179753-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | SIMPSON BIOTECH CO., LTD. (TW) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179753-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | HAVCR2, CYP51A1, NPC1 | LMNA 3197/4885HSD17B10 462/4885EPHX1 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.