Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 7/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 6/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 7/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.46 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | P2RX6 | O15547 | 1/20 | 0.42 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828312 | 1.00 | P2RX3 (0.47) | P2RX3P2RX1P2RX2P2RY1P2RY2 | |
| SCHEMBL15828310 | 0.86 | P2RX1 (0.63) | P2RX3P2RX1P2RX2P2RY1P2RY2 | |
| SCHEMBL15828228 | 0.86 | P2RX1 (0.63) | P2RX3P2RX1P2RX2P2RY1P2RY2 | |
| SCHEMBL16368058 | 0.83 | P2RY1 (0.44) | P2RX3P2RX1P2RX2P2RY1P2RY2 | |
| SCHEMBL16367992 | 0.82 | P2RX3 (0.45) | P2RX3P2RX1P2RX2P2RY1P2RY2 | |
| SCHEMBL15828308 | 0.82 | TGM2 (0.55) | P2RY2P2RY6 | |
| SCHEMBL15828230 | 0.82 | TGM2 (0.55) | P2RY2P2RY6 | |
| SCHEMBL15070357 | 0.82 | P2RX3 (0.43) | P2RX3P2RX1P2RX2P2RY1P2RY2 | |
| SCHEMBL15070345 | 0.81 | P2RX3 (0.42) | P2RX3P2RX1P2RX2P2RY1P2RY2 | |
| SCHEMBL15070351 | 0.81 | P2RX3 (0.43) | P2RX3P2RX1P2RX2P2RY1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9211300-B2 | 4′-fluoro nucleosides for the treatment of HCV | IDENIX PHARMACEUTICALS LLC (US) | 2015-12-15 | — | — | US | disclosed |
| US-20140178338-A1 | 4'-FLUORO NUCLOSIDES FOR THE TREATMENT OF HCV | UNIVERSITE DE MONTPELLIER (FR) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140178338-A1 | 4'-FLUORO NUCLOSIDES FOR THE TREATMENT OF HCV | FBL, HNRNPLL, SLC28A1 | P2RX3 1685/4885P2RX1 1842/4885P2RX2 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.