Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14041546 | 0.94 | HRH3 (0.56) | HRH3KCNH2ACHERAD52 | |
| SCHEMBL8159902 | 0.91 | HRH3 (0.52) | HRH3ALDH1A1KDM4EKCNH2CYP2D6 | |
| Methylamine SCHEMBL1583273 | 0.87 | HRH3 (0.42) | HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL14553250 | 0.87 | HRH3 (0.61) | HRH3L3MBTL1KCNH2 | |
| SCHEMBL22310345 | 0.85 | HRH3 (0.56) | HRH3ALDH1A1L3MBTL1CYP2D6CYP2C19 | |
| SCHEMBL8229217 | 0.80 | HRH3 (0.48) | HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL14041545 | 0.78 | HRH3 (0.45) | HRH3ALDH1A1KDM4E | |
| SCHEMBL25864036 | 0.77 | — | — | |
| SCHEMBL27292116 | 0.77 | MAPK1 (0.47) | HRH3ALDH1A1KDM4E | |
| SCHEMBL3075744 | 0.76 | HRH3 (0.56) | HRH3KCNH2ACHERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906758-B1 | Zinc-phthalocyanines and corresponding conjugates, their preparation and use in photodynamic therapy and as diagnostic agents | MOLTENI & C (IT) | 2011-04-20 | — | — | EP | claimed |