Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280415 | 0.86 | CNR1 (0.60) | CNR1MEN1KMT2ARAB9AHTT | |
| SCHEMBL14873812 | 0.86 | KMT2A (0.61) | CNR1MEN1KMT2ARAB9AHTT | |
| SCHEMBL15532876 | 0.85 | CNR1 (0.63) | CNR1MEN1KMT2ARAB9AHTT | |
| SCHEMBL9970321 | 0.84 | CNR1 (0.58) | CNR1MEN1KMT2ARAB9AHTT | |
| SCHEMBL23456343 | 0.83 | MEN1 (0.74) | CNR1MEN1KMT2ARAB9AHTT | |
| SCHEMBL14097983 | 0.82 | CNR1 (0.56) | CNR1MEN1KMT2ARAB9AHTT | |
| SCHEMBL16129581 | 0.82 | SIRT1 (0.59) | CNR1MEN1KMT2ARAB9AHTT | |
| SCHEMBL598010 | 0.81 | CNR1 (0.66) | CNR1MEN1KMT2ARAB9AHTT | |
| SCHEMBL30831949 | 0.81 | CNR1 (0.67) | CNR1MEN1KMT2ARAB9AHTT | |
| SCHEMBL15750289 | 0.81 | EPHX1 (0.59) | CNR1RAB9AHTTMAPK1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646441-B1 | CARBOCYCLE-SUBSTITUTED PURINE AND 7-DEAZAPURINE COMPOUNDS | EPIZYME INC (US) | 2015-12-02 | — | — | EP | disclosed |
| WO-2014100662-A1 | DOT1 L INHIBITORS FOR USE IN THE TREATMENT OF LEUKEMIA | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |