Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 4/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1582584 | 0.87 | METAP1 (0.41) | METAP1CYP19A1PIM1CSNK1A1CDK5 | |
| SCHEMBL31046475 | 0.84 | ACHE (0.39) | METAP1CYP19A1PIM1CSNK1A1CDK5 | |
| SCHEMBL5953234 | 0.84 | ACHE (0.39) | METAP1CYP19A1PIM1CSNK1A1CDK5 | |
| SCHEMBL1583328 | 0.83 | METAP1 (0.40) | METAP1CYP19A1PIM1CSNK1A1CDK5 | |
| SCHEMBL7627859 | 0.81 | ACHE (0.62) | METAP1CYP19A1ACHEPARP10PARP11 | |
| SCHEMBL5952774 | 0.80 | METAP1 (0.43) | METAP1CYP19A1ACHE | |
| SCHEMBL9317264 | 0.80 | METAP1 (0.46) | METAP1CYP19A1ACHE | |
| SCHEMBL9971050 | 0.80 | CYP19A1 (0.41) | METAP1CYP19A1PIM1CSNK1A1CDK5 | |
| SCHEMBL15016436 | 0.79 | CYP1A2 (0.42) | METAP1CYP19A1ACHE | |
| SCHEMBL1583277 | 0.79 | METAP1 (0.42) | METAP1CYP19A1ACHEPARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022234-B1 | SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2018-12-26 | — | — | EP | disclosed |
| US-9458254-B2 | Substituted metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458254-B2 | Substituted metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458254-B2 | Substituted metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-10-04 | — | — | US | disclosed |
| EP-3022234-A1 | SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| CN-105377906-A | Substituted metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC | 2016-03-02 | — | — | CN | disclosed |
| WO-2015009479-A1 | SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| US-20150025209-A1 | Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| US-20150025209-A1 | Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| US-20150025209-A1 | Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| EP-0629632-B1 | Polypropylene | MITSUI CHEMICALS INC (JP) | 2000-10-04 | — | — | EP | disclosed |
| CN-1249312-A | Propylene Homopolymer, Propylene Copolymer and Propylene Elastomer | MITSUI CHEMICALS INC (JP) | 2000-04-05 | — | — | CN | disclosed |
| US-5936053-A | RIGIDITY, HEAT RESISTANCE, IMPACT STRENGTH; LOW PROPORTION OF INVERSELY INSERTED PROPYLENE UNITS | MITSUI CHEMICALS, INC. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5723640-A | Transition metal compound having indenyl-containing metallocene | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5710223-A | COORDINATION POLYMERIZATION CATALYSTS FOR PROPYLENE HOMOPOLYMERS AND COPOLYMERS | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| US-5705584-A | COORDINATION CATALYSTS FOR ADDITION POLYMERIZATION OF PROPYLENE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0812854-A2 | Novel transition metal compound, olefin polymerization catalyst comprising said compound, process for olefin polymerization using said catalyst and propylene homo- and copolymer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-5658997-A | USING ZIRCONIUM COMPOUND WITH ALUMINOXANE AND ORGANOALUMINUM COMPOUND | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5629254-A | Substituted indenyl ring containing metallocene catalyst for propylene polymerization process | MITSUI PETROCHEMICAL INDUSTRIES CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0629632-A2 | Novel transition metal compound for use as a polymerization catalyst | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |