Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627859 | 0.81 | ACHE (0.62) | METAP1CYP19A1ACHEHTR2AHTR2C | |
| SCHEMBL5952774 | 0.80 | METAP1 (0.43) | METAP1CYP19A1ACHEAADATHTR1A | |
| SCHEMBL1582991 | 0.80 | METAP1 (0.43) | METAP1CYP19A1ACHE | |
| SCHEMBL1583277 | 0.79 | METAP1 (0.42) | METAP1CYP19A1ACHEHTR1AHTR7 | |
| SCHEMBL6472550 | 0.77 | ACHE (0.66) | METAP1CYP19A1ACHEDRD2HTR2A | |
| SCHEMBL5952468 | 0.76 | ACHE (0.41) | METAP1CYP19A1ACHE | |
| SCHEMBL16230152 | 0.76 | CYP19A1 (0.40) | METAP1CYP19A1ACHEDRD2HTR2A | |
| SCHEMBL16556014 | 0.75 | ACHE (0.41) | METAP1CYP19A1ACHEDRD2HTR2A | |
| SCHEMBL5951285 | 0.75 | METAP1 (0.39) | METAP1CYP19A1ACHEHTR2AHTR2C | |
| SCHEMBL5951960 | 0.75 | HTR7 (0.44) | METAP1CYP19A1ACHEHTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994008954-A1 | ARTHROPODICIDAL SEMICARBAZONES | LAHM, GEORGE, PHILIP | 1994-04-28 | — | — | WO | disclosed |