Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 12/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603886 | 0.85 | GRM2 (0.47) | HRH4GRM2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2527876 | 0.82 | GRM2 (0.43) | GRM2DHFR | |
| SCHEMBL15831822 | 0.82 | RXFP1 (0.58) | HRH4ALDH1A1KDM4ERXFP1ALOX15 | |
| SCHEMBL2527319 | 0.81 | HRH4 (0.61) | HRH4ALDH1A1KDM4ESMN1; SMN2ALOX15 | |
| SCHEMBL15831812 | 0.81 | HRH4 (0.51) | HRH4ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL15831793 | 0.79 | HRH4 (0.61) | HRH4ALDH1A1KDM4ESMN1; SMN2RXFP1 | |
| SCHEMBL6949334 | 0.79 | HRH4 (0.55) | HRH4ALDH1A1KDM4ESMN1; SMN2RXFP1 | |
| SCHEMBL7066926 | 0.78 | HRH4 (0.60) | HRH4ALDH1A1KDM4ESMN1; SMN2RXFP1 | |
| SCHEMBL14781363 | 0.78 | HRH4 (0.60) | HRH4ALDH1A1KDM4ESMN1; SMN2RXFP1 | |
| SCHEMBL2553146 | 0.78 | HRH4 (0.60) | HRH4ALDH1A1KDM4ESMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | GRUENENTHAL GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | TRPV1, TRPV5, TRPV2 | HRH4 45/4885GRM2 685/4885ALDH1A1 2444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.