Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 13/20 | 0.58 |
| ▸ | PPIB | P23284 | 7/20 | 0.56 |
| ▸ | PPIG | Q13427 | 7/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2039280 | 0.78 | PPID (0.73) | PPIDPPIBPPIGEPHX1 | |
| SCHEMBL12643750 | 0.76 | PPIB (0.73) | PPIDPPIBPPIGEPHX1 | |
| SCHEMBL2037719 | 0.75 | PPID (1.00) | PPIDPPIBPPIGEPHX1 | |
| SCHEMBL2053173 | 0.74 | PPID (0.97) | PPIDPPIBPPIGEPHX1 | |
| SCHEMBL2036896 | 0.72 | PPIB (1.00) | PPIDPPIBPPIG | |
| SCHEMBL2037683 | 0.71 | PPID (0.76) | PPIDPPIBPPIGEPHX1 | |
| SCHEMBL2035627 | 0.69 | PPIB (1.00) | PPIDPPIBPPIG | |
| SCHEMBL28056208 | 0.68 | PPID (0.81) | PPIDPPIBPPIG | |
| SCHEMBL14617668 | 0.68 | PPIB (0.59) | PPIDPPIBPPIGEPHX2 | |
| SCHEMBL2038271 | 0.68 | PPID (0.78) | PPIDPPIBPPIGEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | FKBP3, FKBP4, FKBP5 | PPID 73/4885PPIB 51/4885PPIG 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.