SCHEMBL1583334

SCHEMBL1583334

C#CCCC(C(=O)O)N(C)[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25179549 0.69 MMP13 (0.35)
SCHEMBL1583283 0.68 GRIK1 (0.36)
SCHEMBL2549304 0.66
SCHEMBL1583495 0.66
SCHEMBL8141270 0.65
SCHEMBL11897270 0.64 GRIK1 (0.30)
SCHEMBL28850932 0.63
SCHEMBL9611497 0.63 CYP1A2 (0.34) KDM4EALDH1A1HPGD
SCHEMBL15669779 0.63 CA2 (0.54)
SCHEMBL869479 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011041534-A1 FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-04-07 WO disclosed