SCHEMBL1583344

SCHEMBL1583344

ON=CC(O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.44
MAPK1 P28482 1/20 0.44
TSHR P16473 1/20 0.38
ALDH1A1 P00352 2/20 0.37
GAA P10253 2/20 0.37
MAPT P10636 1/20 0.37
KDM4E B2RXH2 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37
HIF1A Q16665 1/20 0.37
CYP2D6 P10635 1/20 0.36
SRC P12931 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1583342 1.00 LMNA (0.44) LMNAMAPK1TSHRALDH1A1GAA
SCHEMBL25620430 0.83 LMNA (0.41) LMNAMAPK1TSHRALDH1A1KDM4E
SCHEMBL4631998 0.78 NPSR1 (0.42) LMNAMAPK1TSHRALDH1A1GAA
SCHEMBL4632000 0.78 NPSR1 (0.42) LMNAMAPK1TSHRALDH1A1GAA
SCHEMBL8777389 0.76 LMNA (0.45) LMNAMAPK1TSHRALDH1A1MAPT
SCHEMBL2912526 0.74 TRPA1 (0.47) LMNAMAPK1ALDH1A1MAPTKDM4E
SCHEMBL5664847 0.74 TSHR (0.44) LMNAMAPK1TSHRALDH1A1GAA
SCHEMBL6630642 0.74 LMNA (0.38) LMNAMAPK1TSHRALDH1A1GAA
SCHEMBL2912522 0.74 TRPA1 (0.47) LMNAMAPK1ALDH1A1MAPTKDM4E
SCHEMBL28638696 0.74 DPP4 (0.44) LMNAMAPK1ALDH1A1KDM4EADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200367495-A1 METHOD FOR INDUCING ACQUIRED RESISTANCE IN A PLANT HEINRICH HEINE UNIVERSITAET DUESSELDORF (DE) 2020-11-26 US disclosed
EP-3709809-A1 METHOD FOR INDUCING ACQUIRED RESISTANCE IN A PLANT Heinrich-Heine-Universität Düsseldorf (DE) 2020-09-23 EP disclosed
CN-110714213-A Cyanide-free alkaline cuprous copper electroplating complexing agent 武汉奥邦表面技术有限公司 2020-01-21 CN disclosed
WO-2012126059-A1 NOVEL STOCK FEED CROP PLANT MONASH UNIVERSITY (AU) 2012-09-27 WO disclosed
EP-2486404-A1 METABOLIC BIOMARKERS OF DRUG-INDUCED CARDIOTOXICITY Wisconsin Alumni Research Foundation (US) 2012-08-15 EP disclosed
WO-2011044253-A1 METABOLIC BIOMARKERS OF DRUG-INDUCED CARDIOTOXICITY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-04-14 WO disclosed
US-20110081675-A1 Metabolic Biomarkers Of Drug-Induced Cardiotoxicity WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-04-07 US disclosed
US-20080222754-A1 Methods of Modulating Glucosinolate Production in Plants THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2008-09-11 US disclosed
US-6649814-B2 Nucleotide sequences coding enzymatic polypeptide for use in the generation of disease, pest and insect resistant plants SYNGENTA PARTICIPATIONS AG (CH) 2003-11-18 US disclosed
US-20030041346-A1 Cytochrome P450 monooxygenases HALKIER BARBARA A (DK) 2003-02-27 US disclosed
EP-1246906-A2 P450 MONOOXYGENASES OF THE CYP79 FAMILY Syngenta Participations AG (CH) 2002-10-09 EP disclosed
EP-1200610-A1 GENE CONTROLLING SHOOT BRANCHING IN PLANTS Institute of Molecular Agrobiology (SG) 2002-05-02 EP disclosed
WO-2001090388-A1 GENE CONTROLLING SHOOT BRANCHING IN PLANTS INSTITUTE OF MOLECULAR AGROBIOLOGY (SG) 2001-11-29 WO disclosed
WO-2001051622-A2 P450 MONOOXYGENASES OF THE CYP79 FAMILY SYNGENTA PARTICIPATIONS AG (CH) 2001-07-19 WO disclosed
EP-0970191-A2 CYTOCHROME P450 MONOOXYGENASES Novartis AG (CH) 2000-01-12 EP disclosed
WO-1998040470-A2 CYTOCHROME P450 MONOOXYGENASES NOVARTIS AG (CH) 1998-09-17 WO disclosed