Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 18/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15833573 | 0.88 | GRIN2B (0.44) | GRIN2B | |
| SCHEMBL15833581 | 0.77 | NTRK1 (0.41) | — | |
| SCHEMBL5068124 | 0.75 | MKNK2 (0.42) | — | |
| SCHEMBL15833685 | 0.73 | LMNA (0.42) | GRIN2B | |
| SCHEMBL15833479 | 0.73 | KMT2A (0.41) | GRIN2B | |
| SCHEMBL15835890 | 0.72 | GRIN2B (0.46) | GRIN2B | |
| SCHEMBL24110604 | 0.72 | HTR2C (0.47) | — | |
| SCHEMBL15833488 | 0.70 | MAPK13 (0.39) | — | |
| SCHEMBL25299990 | 0.70 | MKNK2 (0.36) | — | |
| SCHEMBL24110586 | 0.70 | MKNK2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014100764-A2 | METHODS OF INHIBITING PRMT5 | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014100695-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |