SCHEMBL24110604

SCHEMBL24110604

CN(C)CCn1ccc2cncnc21

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.47
HTR2A P28223 3/20 0.47
HTR1D P28221 9/20 0.44
MKNK2 Q9HBH9 2/20 0.38
EGFR P00533 3/20 0.36
MTNR1A P48039 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15833488 0.80 MAPK13 (0.39) MKNK2
SCHEMBL13195335 0.79 MKNK2 (0.40) MKNK2EGFRMTNR1A
SCHEMBL2173797 0.79 MKNK2 (0.40) MKNK2EGFRMTNR1A
SCHEMBL25818492 0.79 MKNK2 (0.40) MKNK2EGFRMTNR1A
SCHEMBL5068124 0.78 MKNK2 (0.42) HTR2CHTR2AMKNK2EGFR
SCHEMBL24109812 0.77 HTR2C (0.47) HTR2CHTR2AHTR1DEGFR
SCHEMBL3892738 0.76 HTR2A (0.57) HTR2CHTR2AHTR1DMTNR1A
SCHEMBL24110249 0.76 HTR2C (0.52) HTR2CHTR2AHTR1DEGFR
SCHEMBL25299990 0.76 MKNK2 (0.36) HTR2CHTR2AMKNK2EGFR
SCHEMBL24110362 0.76 MKNK2 (0.36) HTR2CHTR2AMKNK2EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219969-A1 ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. 2023-07-13 US disclosed
US-20230219969-A1 ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. 2023-07-13 US disclosed
US-20230219969-A1 ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. 2023-07-13 US disclosed
WO-2021252692-A1 ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. (US) 2021-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219969-A1 ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF GAP43, SLC18A2, PNMT HTR2C 35/4885HTR2A 10/4885HTR1D 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.