SCHEMBL158348

SCHEMBL158348

O=C(c1ccccc1)c1ccc(F)cc1F

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
KMT2A Q03164 2/20 0.50
GAA P10253 2/20 0.50
ABCC9 O60706 1/20 0.50
ABCC8 Q09428 1/20 0.50
KCNJ11 Q14654 1/20 0.50
KCNJ8 Q15842 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
ADORA2A P29274 1/20 0.50
ADORA1 P30542 1/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
SRD5A2 P31213 1/20 0.49
AKR1C3 P42330 1/20 0.48
ALDH1A1 P00352 2/20 0.48
ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29765677 1.00 CES2 (0.59) CES2CES1KMT2AGAAABCC9
SCHEMBL29880739 0.88 CES2 (0.63) CES2CES1KMT2AKDM4ESRD5A2
SCHEMBL8609990 0.88 CES2 (0.63) CES2CES1KMT2AKDM4ESRD5A2
SCHEMBL5072461 0.87 HPGD (0.54) KMT2AGAAABCC9ABCC8KCNJ11
SCHEMBL333382 0.85 CES2 (0.59) CES2CES1KMT2AGAAKDM4E
SCHEMBL29367263 0.85 CES2 (0.59) CES2CES1KMT2AGAAKDM4E
SCHEMBL14431511 0.85 CES2 (0.59) CES2CES1KMT2AKDM4EMEN1
SCHEMBL13291390 0.83 CES2 (0.74) CES2CES1KMT2AL3MBTL1MAPK14
SCHEMBL30070815 0.83 GAA (0.68) KMT2AGAAABCC9ABCC8KCNJ11
SCHEMBL5375567 0.83 MEN1 (0.68) KMT2AGAAABCC9ABCC8KCNJ11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114950159-B Preparation method of aromatic polymer separation membrane based on super acid catalysis 南京工业大学 2023-06-06 CN claimed
CN-115646402-A Processing system and method for 2, 4-difluorobenzophenone 江苏万隆化学有限公司 2023-01-31 CN claimed
CN-114950159-A Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation 南京工业大学 2022-08-30 CN claimed
CN-114685387-A Flutriafol hapten, antigen, antibody, detection device, preparation and application thereof 深圳市易瑞生物技术股份有限公司 2022-07-01 CN claimed
CN-109580598-B Analysis method for determining trace acid value in fluoroketone by visual colorimetry 中化蓝天氟材料有限公司 2021-09-14 CN claimed
CN-109580598-A A kind of optical colorimetry measures the analysis method of micro acid value in fluorinated ketones contained 浙江化工院科技有限公司 2019-04-05 CN claimed
US-9707510-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2017-07-18 US claimed
CN-105541568-B The preparation method and device of polymethoxy dimethyl ether reaction raw materials 凯瑞环保科技股份有限公司 2017-06-13 CN claimed
CN-105541568-A Preparation method and device of polymethoxy dimethyl ether reaction raw material KAIRUI ENV PROT TECH CO LTD 2016-05-04 CN claimed
EP-2611519-A2 REGENERABLE SOLVENT MIXTURES WITH NITROGENOUS BASE FOR ACID-GAS SEPARATION Research Triangle Institute (US) 2013-07-10 EP claimed
US-20130164200-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2013-06-27 US claimed
WO-2012031281-A2 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2012-03-08 WO claimed
CN-101570591-A Polyether-ether-ketone polymer and preparation method thereof UNIV HEBEI TECHNOLOGY (CN) 2009-11-04 CN claimed
CN-101429177-A Process for producing bactericide of flutriafol midbody JIANGSU SEVENCONTINENT GREEN C (CN) 2009-05-13 CN claimed
CN-1239722-A Synthesis of cyclic aryl ether ketone polymer UNIV JILIN (CN) 1999-12-29 CN claimed
US-12427471-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (NC) 2025-09-30 US disclosed
WO-2025059098-A2 PHOTOCATALYTIC CARBOXYLATION OF SUBSTRATES WITH CARBON OXIDE NEW IRIDIUM INC. (US) 2025-03-20 WO disclosed
US-4636557-A Process for the preparation of aromatic polyethers with mixture of carbonate catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1987-01-13 US disclosed
EP-0143407-B1 PROCESS FOR PREPARING AROMATIC POLYETHERS HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-12 EP disclosed
EP-0143407-A2 Process for preparing aromatic polyethers HOECHST AKTIENGESELLSCHAFT (DE) 1985-06-05 EP disclosed