Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TPMT | P51580 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580812 | 0.91 | KMT2A (0.58) | KMT2ALMNACA5AHMGB1CXCL12 | |
| SCHEMBL1950244 | 0.89 | CA12 (0.48) | LMNATPMTCA5AHMGB1CXCL12 | |
| SCHEMBL11762568 | 0.86 | TPMT (0.55) | LMNATPMTCA5AAKR1C3AKR1C2 | |
| SCHEMBL9350174 | 0.86 | TPMT (0.55) | LMNATPMTCA5AAKR1C3AKR1C2 | |
| SCHEMBL27646038 | 0.85 | ALDH1A1 (0.52) | KMT2ALMNATPMTCA5AAKR1C3 | |
| SCHEMBL13898756 | 0.85 | CREBBP (0.51) | KMT2ALMNATPMTCA5AAKR1C3 | |
| SCHEMBL14067800 | 0.81 | KMT2A (0.48) | KMT2ALMNACA5AHMGB1CXCL12 | |
| SCHEMBL13898622 | 0.80 | CA2 (0.38) | KMT2ALMNATPMTCA5AAKR1C3 | |
| SCHEMBL15835579 | 0.79 | DHODH (0.48) | LMNATPMTCA5AAKR1C3AKR1C2 | |
| SCHEMBL27386976 | 0.79 | LCK (0.41) | KMT2ALMNATPMTCA5AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9393548-B2 | Rapid and enhanced activation of microporous coordination polymers by flowing supercritical CO2 | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-07-19 | — | — | US | disclosed |
| US-20140179514-A1 | RAPID AND ENHANCED ACTIVATION OF MICROPOROUS COORDINATION POLYMERS BY FLOWING SUPERCRITICAL CO2 | UNITED STATES DEPARTMENT OF ENERGY | 2014-06-26 | — | — | US | disclosed |