Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1584564 | 0.91 | P2RX7 (0.47) | P2RX7TYRO3MERTKRBP4 | |
| SCHEMBL1583038 | 0.91 | P2RX7 (0.49) | P2RX7TYRO3MERTK | |
| SCHEMBL12720597 | 0.90 | P2RX7 (0.48) | P2RX7TYRO3MERTK | |
| SCHEMBL12720955 | 0.90 | P2RX7 (0.48) | P2RX7TYRO3MERTK | |
| SCHEMBL1584096 | 0.89 | P2RX7 (0.39) | P2RX7TYRO3MERTKRBP4 | |
| SCHEMBL12720664 | 0.89 | P2RX7 (0.40) | P2RX7TYRO3MERTKRBP4 | |
| SCHEMBL1583571 | 0.89 | P2RX7 (0.41) | P2RX7TYRO3MERTK | |
| SCHEMBL12720642 | 0.89 | P2RX7 (0.39) | P2RX7TYRO3MERTK | |
| SCHEMBL12721159 | 0.87 | P2RX7 (0.40) | P2RX7TYRO3MERTK | |
| SCHEMBL1583859 | 0.87 | P2RX7 (0.38) | P2RX7RORCTYRO3MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |