Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 9/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1583891 | 0.83 | USP7 (0.44) | USP7RORCPTGS1PTGS2NR1H3 | |
| SCHEMBL9893228 | 0.80 | USP7 (0.41) | USP7CNR1CNR2RORCPTGS1 | |
| SCHEMBL1583244 | 0.75 | USP7 (0.46) | USP7RORCNR1H3NR1H2 | |
| SCHEMBL3687402 | 0.73 | PIN1 (0.41) | PTGS1PTGS2KMOPOLB | |
| SCHEMBL15766422 | 0.71 | USP7 (0.41) | USP7RORCNR1H3NR1H2 | |
| SCHEMBL1584050 | 0.70 | USP7 (0.41) | USP7RORCNR1H3NR1H2PPARG | |
| SCHEMBL3069553 | 0.70 | KDM4E (0.44) | USP7NR1H3NR1H2CYP1A2POLB | |
| SCHEMBL30871207 | 0.70 | PTGS1 (0.37) | USP7RORCPTGS1PTGS2MEN1 | |
| SCHEMBL15767520 | 0.69 | USP7 (0.42) | USP7NR1H3NR1H2 | |
| SCHEMBL15558634 | 0.69 | PTGS1 (0.66) | PTGS1PTGS2KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |