Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 10/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069553 | 0.87 | KDM4E (0.44) | USP7NR1H3NR1H2BRD4MAPT | |
| SCHEMBL1583891 | 0.84 | USP7 (0.44) | USP7NR1H3NR1H2RORCPPARG | |
| SCHEMBL1583799 | 0.70 | USP7 (0.44) | USP7NR1H3NR1H2RORCPPARG | |
| SCHEMBL9924030 | 0.70 | KDM4E (0.45) | USP7NR1H3NR1H2MAPTRAB9A | |
| SCHEMBL3071037 | 0.70 | RBP4 (0.39) | USP7 | |
| SCHEMBL3063204 | 0.68 | P2RX7 (0.43) | — | |
| SCHEMBL9893228 | 0.68 | USP7 (0.41) | USP7NR1H3NR1H2RORCMAPT | |
| SCHEMBL1583159 | 0.68 | NOTUM (0.40) | MAPTNPC1RAB9A | |
| SCHEMBL13229232 | 0.67 | P2RX7 (0.42) | USP7RORC | |
| SCHEMBL875798 | 0.67 | USP7 (0.43) | USP7NR1H3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |