SCHEMBL15840236

SCHEMBL15840236

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4ccc5c(c43)-c3ccccc3C53c4ccccc4-c4c3ccc3c5ccccc5n(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c43)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DUSP3 P51452 1/20 0.34
KDM4E B2RXH2 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15832138 0.99 DUSP3 (0.34) DUSP3
SCHEMBL20199554 0.98 DUSP3 (0.33) DUSP3
SCHEMBL17282621 0.97 DUSP3 (0.33) DUSP3
SCHEMBL15840144 0.97 DUSP3 (0.33) DUSP3
SCHEMBL15840223 0.96 L3MBTL1 (0.36) DUSP3KDM4EATML3MBTL1
SCHEMBL24078178 0.95 DUSP3 (0.33) DUSP3
SCHEMBL24078478 0.94 DUSP3 (0.32) DUSP3
SCHEMBL2618776 0.94 DUSP3 (0.33) DUSP3KDM4E
SCHEMBL15840207 0.94 DUSP3 (0.31) DUSP3
SCHEMBL25965961 0.93 DUSP3 (0.32) DUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10227528-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2019-03-12 US disclosed
EP-2935276-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-11-01 EP disclosed
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
WO-2014094963-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10227528-B2 Materials for organic electroluminescent devices OR10J3, EPCAM, L1CAM DUSP3 3224/4885KDM4E 2105/4885ATM 2996/4885
US-20150337197-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EML4, L1CAM DUSP3 3107/4885KDM4E 2176/4885ATM 3105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.