Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | LIG1 | P18858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20199552 | 0.99 | L3MBTL1 (0.34) | KDM4EL3MBTL1ATMLMNAMAPT | |
| SCHEMBL20203685 | 0.91 | KDM4E (0.41) | KDM4EL3MBTL1ATMDUSP3HSP90AA1 | |
| SCHEMBL20199809 | 0.91 | KDM4E (0.41) | KDM4EL3MBTL1ATMDUSP3HSP90AA1 | |
| SCHEMBL15840149 | 0.90 | L3MBTL1 (0.46) | KDM4EL3MBTL1ATMMAPTHTT | |
| SCHEMBL15840251 | 0.89 | ALDH1A1 (0.35) | KDM4EL3MBTL1ATMLMNAMAPT | |
| SCHEMBL15840274 | 0.89 | KDM4E (0.39) | KDM4EL3MBTL1ATMDUSP3 | |
| SCHEMBL20199545 | 0.88 | L3MBTL1 (0.45) | KDM4EL3MBTL1ATMMAPTHTT | |
| SCHEMBL15840156 | 0.88 | L3MBTL1 (0.47) | KDM4EL3MBTL1ATMMAPTHTT | |
| SCHEMBL15840166 | 0.88 | KDM4E (0.35) | KDM4EL3MBTL1ATMHTTDUSP3 | |
| SCHEMBL15840159 | 0.88 | L3MBTL1 (0.38) | KDM4EL3MBTL1ATMMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935276-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| WO-2014094963-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |