SCHEMBL15840458

SCHEMBL15840458

NC(=O)CNC(=O)CC[C@H](NC(=O)[C@@H](N)CC(N)=O)C(N)=O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 1/20 0.43
ECE1 P42892 3/20 0.38
PTGS1 P23219 1/20 0.35
GSTK1 Q9Y2Q3 1/20 0.35
DPP4 P27487 1/20 0.34
DPP8 Q6V1X1 1/20 0.34
DPP9 Q86TI2 1/20 0.34
GLO1 Q04760 1/20 0.34
BMP1 P13497 1/20 0.33
ALDH1A1 P00352 1/20 0.31
MMP1 P03956 1/20 0.31
SIRT5 Q9NXA8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15840393 0.82 DPP4 (0.40) NOD1ECE1PTGS1GSTK1DPP4
SCHEMBL5970719 0.78 NOD1 (0.48) NOD1ECE1PTGS1GSTK1GLO1
SCHEMBL6516429 0.77 ECE1 (0.51) NOD1ECE1DPP4DPP8DPP9
SCHEMBL24431379 0.75 NOD1 (0.53) NOD1ECE1PTGS1GSTK1DPP4
SCHEMBL2242130 0.74 DPP4 (0.57) NOD1ECE1PTGS1GSTK1DPP4
SCHEMBL2837128 0.74 ECE1 (0.41) NOD1ECE1DPP4DPP8DPP9
SCHEMBL757140 0.74 CA12 (0.33) ECE1DPP4DPP8DPP9
SCHEMBL2242132 0.74 DPP4 (0.57) NOD1ECE1PTGS1GSTK1DPP4
SCHEMBL1900352 0.74 GSR (0.42) NOD1ECE1DPP8DPP9
SCHEMBL15840382 0.74 DPP7 (0.39) NOD1ECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014095773-A1 PEPTIDES AS OXYTOCIN AGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2014-06-26 WO disclosed