Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.51 |
| ▸ | GRB2 | P62993 | 5/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837128 | 0.88 | ECE1 (0.41) | ECE1PDCD1LG2CD274DPP4DPP8 | |
| SCHEMBL30038644 | 0.87 | ECE1 (0.53) | ECE1GRB2PDCD1LG2CD274DPP4 | |
| SCHEMBL18075525 | 0.86 | ECE1 (0.56) | ECE1PDCD1LG2CD274ITGB2ICAM1 | |
| SCHEMBL15461 | 0.86 | ECE1 (0.56) | ECE1PDCD1LG2CD274ITGB2ICAM1 | |
| SCHEMBL31199039 | 0.85 | DPP4 (0.54) | ECE1GRB2PDCD1LG2CD274DPP4 | |
| SCHEMBL1246595 | 0.82 | ECE1 (0.53) | ECE1PDCD1LG2CD274ITGB2ICAM1 | |
| SCHEMBL7258586 | 0.82 | ECE1 (0.53) | ECE1PDCD1LG2CD274ITGB2ICAM1 | |
| Asparagine SCHEMBL19259348 | 0.82 | ECE1 (0.53) | ECE1PDCD1LG2CD274ITGB2ICAM1 | |
| SCHEMBL7148009 | 0.82 | ECE1 (0.53) | ECE1PDCD1LG2CD274ITGB2ICAM1 | |
| SCHEMBL6852847 | 0.82 | ECE1 (0.53) | ECE1PDCD1LG2CD274ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050164515-A9 | Biological control of nanoparticle nucleation, shape and crystal phase | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2005-07-28 | — | — | US | disclosed |
| EP-0728203-A1 | ANALOGOUS PEPTIDES OF THE INTERNAL IMAGE OF A VIRAL PROTEIN | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1996-08-28 | — | — | EP | disclosed |
| WO-1993017108-A2 | ANALOGOUS PEPTIDES OF THE INTERNAL IMAGE OF A VIRAL PROTEIN | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 1993-09-02 | — | — | WO | disclosed |