Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 15/20 | 1.00 |
| ▸ | MEN1 | O00255 | 14/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 1.00 |
| ▸ | HPGD | P15428 | 7/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 9/20 | 0.81 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.81 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.81 |
| ▸ | RECQL | P46063 | 2/20 | 0.81 |
| ▸ | POLB | P06746 | 3/20 | 0.79 |
| ▸ | XBP1 | P17861 | 1/20 | 0.79 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.79 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.79 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.79 |
| ▸ | PLEC | Q15149 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840653 | 0.91 | KMT2A (0.85) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL15840511 | 0.90 | KMT2A (1.00) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL15840526 | 0.82 | KMT2A (1.00) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL13212128 | 0.81 | MEN1 (1.00) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL15840522 | 0.81 | KMT2A (0.75) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL13212121 | 0.80 | MEN1 (1.00) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL15840627 | 0.78 | MEN1 (1.00) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL15840608 | 0.76 | MEN1 (0.77) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL5401402 | 0.76 | ALDH1A1 (1.00) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL287025 | 0.74 | AKT1 (1.00) | KMT2AMEN1ALDH1A1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | KMT2A 3667/4885MEN1 3121/4885ALDH1A1 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.