Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.53 |
| ▸ | IDH1 | O75874 | 1/20 | 0.52 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.51 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840735 | 0.93 | ALDH1A1 (0.61) | PPIAALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL15840733 | 0.86 | PPIA (0.71) | PPIAALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL15840641 | 0.85 | PPIA (0.74) | PPIAALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL15840818 | 0.84 | PPIA (0.74) | PPIAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL13784990 | 0.82 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL15840678 | 0.81 | MAPT (0.72) | PPIAALDH1A1KMT2AMEN1GAA | |
| SCHEMBL6812397 | 0.79 | ALDH1A1 (0.57) | PPIAALDH1A1KMT2AMEN1GAA | |
| SCHEMBL6442535 | 0.79 | GAA (0.67) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL15840660 | 0.78 | PPIA (0.62) | PPIAALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL15840705 | 0.77 | PPIA (0.78) | PPIAALDH1A1KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | PPIA 1884/4885ALDH1A1 4348/4885KMT2A 3667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.