Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.55 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840660 | 0.92 | PPIA (0.62) | PPIALMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL15840685 | 0.89 | PPIA (0.72) | PPIALMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL15840666 | 0.88 | LMNA (0.63) | PPIALMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL15840673 | 0.85 | PPIA (0.67) | PPIALMNAHTTMAPK1MEN1 | |
| SCHEMBL15840733 | 0.84 | PPIA (0.71) | PPIALMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL15840705 | 0.84 | PPIA (0.78) | PPIALMNAMAPK1ALOX15MEN1 | |
| SCHEMBL15840714 | 0.82 | HTT (0.67) | LMNAHTTSMN1; SMN2MAPK1ALOX15 | |
| SCHEMBL15840723 | 0.82 | FFAR4 (0.67) | PPIALMNAHTTSMN1; SMN2MAPK1 | |
| SCHEMBL15840818 | 0.81 | PPIA (0.74) | PPIALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL15840655 | 0.81 | ALDH1A1 (0.71) | PPIALMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | PPIA 1884/4885LMNA 2183/4885HTT 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.