Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCNO | P22674 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1583648 | 0.98 | ALDH1A1 (0.40) | ALDH1A1GAATDP1POLBL3MBTL1 | |
| SCHEMBL3775820 | 0.77 | HSD17B10 (0.51) | ALDH1A1GAATDP1POLBL3MBTL1 | |
| SCHEMBL1583412 | 0.72 | KDM4C (0.44) | ALDH1A1GAATDP1POLBL3MBTL1 | |
| SCHEMBL1583593 | 0.72 | TDP1 (0.44) | ALDH1A1GAATDP1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1583585 | 0.71 | KDM4C (0.43) | ALDH1A1GAATDP1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1583289 | 0.71 | KDM4C (0.43) | ALDH1A1GAATDP1POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1583239 | 0.71 | ATM (0.45) | ALDH1A1GAATDP1POLBL3MBTL1 | |
| SCHEMBL19913877 | 0.70 | AR (0.50) | ALDH1A1L3MBTL1GRM4RAB9ASMN1; SMN2 | |
| SCHEMBL19913871 | 0.70 | CRBN (0.54) | ALDH1A1POLBGRM4KDM4EHSD17B10 | |
| SCHEMBL8473403 | 0.69 | ALDH1A1 (0.46) | ALDH1A1GAATDP1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | claimed |