Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3775820 | 0.73 | HSD17B10 (0.51) | ALDH1A1GAAKDM4CTDP1POLB | |
| SCHEMBL6411615 | 0.69 | CRBN (0.46) | ALDH1A1GAATDP1POLBHSD17B10 | |
| SCHEMBL1584075 | 0.69 | ALDH1A1 (0.41) | ALDH1A1GAAKDM4CTDP1POLB | |
| SCHEMBL30491903 | 0.68 | PDE3B (0.46) | ALDH1A1GAATDP1HSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL1583648 | 0.68 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4CTDP1POLB | |
| SCHEMBL1583412 | 0.68 | KDM4C (0.44) | ALDH1A1GAAKDM4CTDP1POLB | |
| SCHEMBL29135322 | 0.68 | TDP1 (0.51) | ALDH1A1GAAKDM4CTDP1POLB | |
| SCHEMBL2628993 | 0.68 | L3MBTL1 (0.53) | ALDH1A1GAAKDM4CTDP1POLB | |
| Hydrochloric Acid SCHEMBL1583289 | 0.67 | KDM4C (0.43) | ALDH1A1GAAKDM4CTDP1POLB | |
| Hydrochloric Acid SCHEMBL1583585 | 0.67 | KDM4C (0.43) | ALDH1A1GAAKDM4CTDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299360-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HENGRUI PHARMACEUTICALS CO., LTD (CN) | 2024-09-12 | — | — | US | disclosed |
| US-6004963-A | TUMOR NECROSIS FACTOR RELEASE INHIBITORS; IMMUNOMODULATORS | GRUENENTHAL GMBH (DE) | 1999-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240299360-A1 | ADAMTS INHIBITORS, PREPARATION METHODS AND MEDICINAL USES THEREOF | ADAMTS5, ADAMTS4, ADAMTS1 | ALDH1A1 1671/4885GAA 449/4885KDM4C 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.