Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 15/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464550 | 0.86 | CREBBP (0.75) | CREBBPMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15840609 | 0.83 | STAT3 (0.74) | CREBBPMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15840770 | 0.81 | MAPT (0.62) | CREBBPMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15840686 | 0.75 | ALDH1A1 (0.51) | CREBBPMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15840752 | 0.75 | CREBBP (0.74) | CREBBPMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15840684 | 0.75 | MAPT (0.64) | CREBBPMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL838117 | 0.74 | ALDH1A1 (0.47) | CREBBPMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15840695 | 0.73 | MAPT (0.74) | CREBBPMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15840778 | 0.73 | MAPT (0.60) | CREBBPMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9879088 | 0.72 | GAA (0.75) | MAPTKMT2ASMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | CREBBP 1243/4885MAPT 1076/4885ALDH1A1 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.