Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.75 |
| ▸ | NAMPT | P43490 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 10/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | XBP1 | P17861 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879098 | 0.83 | MEN1 (0.65) | GAANAMPTMAPTKMT2AMEN1 | |
| SCHEMBL9878068 | 0.83 | MEN1 (0.65) | GAANAMPTMAPTKMT2AMEN1 | |
| SCHEMBL9879486 | 0.80 | KMT2A (1.00) | GAAMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9879803 | 0.79 | MEN1 (0.60) | GAANAMPTMAPTKMT2AMEN1 | |
| SCHEMBL9879083 | 0.79 | MEN1 (0.56) | GAANAMPTMAPTKMT2AMEN1 | |
| SCHEMBL9879255 | 0.78 | MEN1 (0.55) | GAANAMPTMAPTKMT2AMEN1 | |
| SCHEMBL9879392 | 0.78 | KMT2A (0.74) | GAANAMPTMAPTKMT2AMEN1 | |
| SCHEMBL9878162 | 0.76 | MEN1 (0.52) | GAANAMPTMAPTKMT2AMEN1 | |
| SCHEMBL9878159 | 0.76 | MEN1 (0.52) | GAANAMPTMAPTKMT2AMEN1 | |
| SCHEMBL9879258 | 0.76 | MAPT (0.62) | GAANAMPTMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |