Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAT2A | P31153 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840764 | 0.89 | ADORA1 (0.83) | ADORA1TP53MAPTGAAALDH1A1 | |
| SCHEMBL15840693 | 0.80 | ADORA1 (1.00) | ADORA1TP53MAPTGAAALDH1A1 | |
| SCHEMBL15840683 | 0.76 | TP53 (0.67) | ADORA1TP53MAPTGAAALDH1A1 | |
| SCHEMBL11704650 | 0.75 | MAPT (1.00) | ADORA1TP53MAPTGAAALDH1A1 | |
| SCHEMBL3486780 | 0.75 | MAPT (0.68) | ADORA1TP53MAPTGAAALDH1A1 | |
| SCHEMBL3487204 | 0.72 | MAPT (0.68) | ADORA1TP53MAPTGAAALDH1A1 | |
| SCHEMBL15840839 | 0.71 | ALDH1A1 (0.62) | ADORA1TP53MAPTGAAALDH1A1 | |
| SCHEMBL7027700 | 0.71 | MAPT (0.62) | ADORA1TP53MAPTGAAALDH1A1 | |
| SCHEMBL11705840 | 0.71 | POLB (0.74) | ADORA1TP53MAPTGAAALDH1A1 | |
| SCHEMBL5218874 | 0.71 | TP53 (0.77) | ADORA1TP53MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | ADORA1 4330/4885TP53 230/4885MAPT 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.