Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | GAA | P10253 | 4/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | MAT2A | P31153 | 1/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11704650 | 0.81 | MAPT (1.00) | MAPTGAATP53MAT2AADORA1 | |
| SCHEMBL3487204 | 0.81 | MAPT (0.68) | MAPTGAATP53MAT2AADORA1 | |
| SCHEMBL11436371 | 0.80 | ALDH1A1 (0.63) | MAPTGAATP53MAT2AADORA1 | |
| SCHEMBL15840764 | 0.80 | ADORA1 (0.83) | MAPTGAATP53MAT2AADORA1 | |
| SCHEMBL11705840 | 0.79 | POLB (0.74) | MAPTGAATP53MAT2AADORA1 | |
| SCHEMBL5223547 | 0.79 | TP53 (0.72) | MAPTGAATP53MAT2AADORA1 | |
| SCHEMBL11706250 | 0.78 | MAPT (0.65) | MAPTGAATP53MAT2AADORA1 | |
| SCHEMBL24109317 | 0.78 | MAT2A (0.61) | MAPTGAATP53MAT2AADORA1 | |
| SCHEMBL7027700 | 0.76 | MAPT (0.62) | MAPTGAATP53MAT2AADORA1 | |
| SCHEMBL11707237 | 0.76 | GAA (0.69) | MAPTGAATP53MAT2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100507-B1 | QUINAZOLINE DERIVATIVES CAPABLE OF INHIBITING CYTOKININ SIGNALING | SUMITOMO CHEMICAL CO (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-8722580-B2 | Agent for inhibiting cytokinin signaling | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20100056377-A1 | AGENT FOR INHIBITING CYTOKININ SIGNALING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| CN-101588716-A | Substance capable of inhibiting cytokinin signaling | SUMITOMO CHEMICAL CO (JP) | 2009-11-25 | — | — | CN | disclosed |
| EP-2100507-A1 | SUBSTANCE CAPABLE OF INHIBITING CYTOKININ SIGNALING | Sumitomo Chemical Company, Limited (JP) | 2009-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056377-A1 | AGENT FOR INHIBITING CYTOKININ SIGNALING | CROCC, STAT3, GRK6 | MAPT 4826/4885GAA 3573/4885TP53 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.