Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.41 |
| ▸ | RORA | P35398 | 7/20 | 0.41 |
| ▸ | RORC | P51449 | 7/20 | 0.41 |
| ▸ | RORB | Q92753 | 7/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840891 | 0.87 | PGR (0.39) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL17229161 | 0.77 | PGR (0.39) | PGRRORARORCRORBNR1H3 | |
| SCHEMBL15829288 | 0.74 | PGR (0.41) | PGRRORARORCRORBNR1H3 | |
| SCHEMBL15427721 | 0.72 | PDE2A (0.34) | METAP2 | |
| SCHEMBL19735266 | 0.70 | KDM4E (0.50) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL15840892 | 0.69 | KDM4E (0.31) | ALDH1A1KDM4EHPGD | |
| SCHEMBL15428249 | 0.68 | KDM4E (0.36) | ALDH1A1MAPTNPSR1KDM4EHPGD | |
| SCHEMBL19669302 | 0.68 | PGR (0.38) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL26936077 | 0.67 | KDM4E (0.43) | PGRRORARORCRORBALDH1A1 | |
| SCHEMBL15840934 | 0.67 | PRKDC (0.43) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935291-B1 | IRIDIUM COMPLEXES USED IN OLIGOMERS, POLYMERS OR DENDRIMERS IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-10-16 | — | — | EP | disclosed |
| US-20150349277-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-12-03 | — | — | US | disclosed |
| US-20150349277-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-12-03 | — | — | US | disclosed |
| WO-2014094960-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150349277-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | PGR 3351/4885RORA 3670/4885RORC 2492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.