Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | EDNRB | P24530 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12550536 | 0.72 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL14616986 | 0.72 | MEN1 (0.55) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL13917751 | 0.70 | EDNRA (0.43) | EDNRAMEN1KMT2AEDNRBALDH1A1 | |
| SCHEMBL7852876 | 0.69 | EDNRA (0.71) | EDNRAMEN1KMT2AEDNRBCYP2C19 | |
| SCHEMBL11483539 | 0.69 | EDNRA (0.71) | EDNRAMEN1KMT2AEDNRBCYP2C19 | |
| SCHEMBL15840986 | 0.68 | MEN1 (0.41) | EDNRAMEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL28435319 | 0.67 | EDNRA (0.56) | EDNRAMEN1KMT2AEDNRBALDH1A1 | |
| SCHEMBL5593897 | 0.67 | POLB (0.52) | EDNRAMEN1KMT2AEDNRB | |
| SCHEMBL14433696 | 0.67 | EDNRA (0.78) | EDNRAMEN1KMT2AEDNRBALDH1A1 | |
| SCHEMBL13589970 | 0.67 | EDNRA (0.78) | EDNRAMEN1KMT2AEDNRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935291-B1 | IRIDIUM COMPLEXES USED IN OLIGOMERS, POLYMERS OR DENDRIMERS IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-10-16 | — | — | EP | disclosed |
| US-20150349277-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-12-03 | — | — | US | disclosed |
| US-20150349277-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2015-12-03 | — | — | US | disclosed |
| US-20150333280-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-11-19 | — | — | US | disclosed |
| US-20150333280-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-11-19 | — | — | US | disclosed |
| WO-2014094960-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014094961-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150333280-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | EDNRA 3142/4885MEN1 989/4885KMT2A 2922/4885 |
| US-20150349277-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | EDNRA 3142/4885MEN1 989/4885KMT2A 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.