Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435319 | 0.78 | EDNRA (0.56) | EDNRAEDNRBALDH1A1POLBCYP2C19 | |
| SCHEMBL28225287 | 0.77 | EDNRA (0.37) | EDNRAEDNRBALDH1A1CYP2C9POLB | |
| SCHEMBL5593897 | 0.73 | POLB (0.52) | EDNRAEDNRBTSHRPOLBMEN1 | |
| SCHEMBL661008 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTNPSR1KDM1A | |
| SCHEMBL13603804 | 0.71 | EDNRB (0.48) | EDNRAEDNRBALDH1A1CYP2C9POLB | |
| SCHEMBL17686896 | 0.70 | HTR2A (0.36) | EDNRAEDNRBALDH1A1CYP2C9TSHR | |
| SCHEMBL15840925 | 0.70 | EDNRA (0.47) | EDNRAEDNRBALDH1A1CYP3A4MAPT | |
| SCHEMBL17686907 | 0.70 | EDNRA (0.42) | EDNRAEDNRBCYP2C9TSHRPOLB | |
| SCHEMBL1812009 | 0.69 | TSHR (0.45) | TSHRNPSR1 | |
| SCHEMBL10355854 | 0.69 | EDNRA (0.50) | EDNRAEDNRBALDH1A1TSHRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090061267-A1 | POWER DEVICE AND OXYGEN GENERATOR | BATTELLE MEMORIAL INSTITUTE (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090061267-A1 | POWER DEVICE AND OXYGEN GENERATOR | BATTELLE MEMORIAL INSTITUTE (US) | 2009-03-05 | — | — | US | disclosed |