SCHEMBL15844488

SCHEMBL15844488

CCCCCCCC1C(=O)c2ccccc2-c2ccccc2C1=O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.44
CES1 P23141 2/20 0.42
CDC25A P30304 1/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15845072 1.00 PTPN1 (0.44) PTPN1CES1CDC25AMEN1NPC1
SCHEMBL1325541 0.96 RAB9A (0.44) PTPN1MEN1NPC1POLBGAA
SCHEMBL11884237 0.85 ALDH1A1 (0.40) PTPN1MEN1NPC1RAB9AKMT2A
SCHEMBL28085412 0.79 PTPN1 (0.40) PTPN1NR1H2NR1H3
SCHEMBL28240950 0.79 PTPN1 (0.40) PTPN1NR1H2NR1H3
SCHEMBL30006748 0.76 PTPN1 (0.44) PTPN1NR1H2NR1H3
SCHEMBL3451423 0.76 ALDH1A1 (0.38) RAB9AALDH1A1HPGD
SCHEMBL6060938 0.76 HTR2A (0.54)
SCHEMBL6060915 0.76 HTR2A (0.54)
SCHEMBL6061312 0.76 HTR2A (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10033019-B2 Organic light-emitting composition, device and method CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2018-07-24 US disclosed
US-20140183469-A1 ORGANIC LIGHT-EMITTING COMPOSITION, DEVICE AND METHOD SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2014-07-03 US disclosed