Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1584689 | 0.94 | PPARA (0.56) | ALDH1A1POLBMAPTSMN1; SMN2USP2 | |
| SCHEMBL22221443 | 0.89 | PPARA (0.54) | ALDH1A1POLBMAPTSMN1; SMN2USP2 | |
| SCHEMBL1584416 | 0.87 | PPARA (0.52) | ALDH1A1POLBMAPTSMN1; SMN2USP2 | |
| SCHEMBL1583983 | 0.86 | PPARA (0.51) | ALDH1A1POLBMAPTSMN1; SMN2USP2 | |
| SCHEMBL12707617 | 0.86 | PPARA (0.51) | ALDH1A1POLBMAPTSMN1; SMN2USP2 | |
| SCHEMBL12707622 | 0.85 | PPARA (0.50) | ALDH1A1POLBMAPTSMN1; SMN2USP2 | |
| SCHEMBL1584444 | 0.85 | PPARA (0.50) | ALDH1A1POLBMAPTSMN1; SMN2USP2 | |
| SCHEMBL1584133 | 0.85 | PPARA (0.59) | ALDH1A1POLBMAPTSMN1; SMN2USP2 | |
| SCHEMBL23903287 | 0.82 | ALDH1A1 (0.57) | ALDH1A1POLBMAPTSMN1; SMN2USP2 | |
| SCHEMBL1585228 | 0.82 | POLB (0.58) | ALDH1A1POLBMAPTSMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044141-A1 | FATTY ACID FIBRATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2011-04-14 | — | — | WO | disclosed |
| US-20110082210-A1 | FATTY ACID FIBRATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082210-A1 | FATTY ACID FIBRATE DERIVATIVES AND THEIR USES | FABP1, PPARA, FABP4 | ALDH1A1 857/4885POLB 3386/4885MAPT 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.