Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.77 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233554 | 0.87 | SLC22A12 (1.00) | SLC22A12CYSLTR1CYSLTR2XDHKMT2A | |
| SCHEMBL1584874 | 0.80 | SLC22A12 (0.48) | SLC22A12CYSLTR1CYSLTR2 | |
| SCHEMBL12723071 | 0.78 | SLC22A12 (0.46) | SLC22A12 | |
| SCHEMBL1248713 | 0.74 | SLC22A12 (0.68) | SLC22A12CYSLTR1CYSLTR2XDHGP6 | |
| SCHEMBL13113060 | 0.71 | XDH (0.85) | SLC22A12CYSLTR1CYSLTR2XDHGP6 | |
| SCHEMBL1628598 | 0.69 | GP6 (0.66) | SLC22A12XDHKMT2AGP6 | |
| SCHEMBL13113378 | 0.67 | GP6 (0.68) | SLC22A12CYSLTR1CYSLTR2GRM2XDH | |
| SCHEMBL6245949 | 0.66 | GRM2 (0.54) | SLC22A12CYSLTR1CYSLTR2GRM2GP6 | |
| SCHEMBL12367 | 0.66 | GP6 (0.66) | SLC22A12XDHGP6 | |
| SCHEMBL6246206 | 0.66 | GRM2 (0.79) | CYSLTR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488020-B1 | 3-SUBSTITUTED COMPOUNDS FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORP (US) | 2016-12-14 | — | — | EP | disclosed |
| EP-2488020-A1 | 3-SUBSTITUTED COMPOUNDS FOR REDUCING URIC ACID | Wellstat Therapeutics Corporation (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046800-A1 | 3-SUBSTITUTED COMPOUNDS FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORPORATION (US) | 2011-04-21 | — | — | WO | disclosed |