Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31571027 | 0.97 | P2RX7 (0.47) | P2RX7FPR2DDB1CRBNHPGD | |
| SCHEMBL29980296 | 0.96 | P2RX7 (0.48) | P2RX7FPR2DDB1CRBNHPGD | |
| SCHEMBL1583284 | 0.95 | P2RX7 (0.46) | P2RX7FPR2DDB1CRBNHPGD | |
| Heptane SCHEMBL31571107 | 0.91 | P2RX7 (0.42) | P2RX7FPR2DDB1CRBNHPGD | |
| SCHEMBL25202856 | 0.89 | DDB1 (0.41) | P2RX7FPR2DDB1CRBNHPGD | |
| SCHEMBL15000449 | 0.89 | USP2 (0.47) | P2RX7FPR2DDB1CRBNMAPT | |
| SCHEMBL6895303 | 0.86 | MAPT (0.41) | P2RX7FPR2DDB1CRBNMAPT | |
| SCHEMBL6895307 | 0.86 | MAPT (0.41) | P2RX7FPR2DDB1CRBNMAPT | |
| SCHEMBL28437919 | 0.83 | NR1H2 (0.43) | DDB1CRBNMAPTALDH1A1TP53 | |
| SCHEMBL15770892 | 0.82 | FPR2 (0.47) | FPR2HPGDMAPTBACE1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |