SCHEMBL15848165

SCHEMBL15848165

CCO[SiH](CCc1cccc2c1ccc1ccccc12)OCC

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 1/20 0.41
NQO2 P16083 1/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2D6 P10635 1/20 0.36
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP2A6 P11509 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CDYL Q9Y232 1/20 0.35
MTNR1A P48039 2/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
AKR1B1 P15121 1/20 0.35
HTR2A P28223 1/20 0.35
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15848457 0.91 CYP1A2 (0.43) NQO2CYP1A2CYP2C19CYP2D6ALDH1A1
SCHEMBL15848402 0.85 HPRT1 (0.44) HPRT1NQO2CYP1A2CYP2C19CYP2D6
SCHEMBL15848514 0.81 HTR2A (0.38) NQO2MTNR1AAKR1B1HTR2A
SCHEMBL15848432 0.81 KMT2A (0.47) CYP1A2CYP2D6ALDH1A1HSD17B10TSHR
SCHEMBL11745876 0.77 HPRT1 (0.54) HPRT1NQO2CYP1A2CYP2C19CYP2D6
SCHEMBL598995 0.77 HPRT1 (0.54) HPRT1NQO2CYP1A2CYP2C19CYP2D6
SCHEMBL15848033 0.76 HPRT1 (0.48) HPRT1NQO2CYP1A2CYP2C19CYP2D6
SCHEMBL12274770 0.74 CYP1A2 (0.46) NQO2CYP1A2CYP2C19CYP2D6TDP1
SCHEMBL6850271 0.74 CYP1A2 (0.46) NQO2CYP1A2CYP2C19CYP2D6ALDH1A1
SCHEMBL285473 0.74 HPRT1 (0.50) HPRT1NQO2CYP1A2CYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150344735-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device DOW CORNING TORAY CO., LTD. (JP) 2015-12-03 US disclosed
US-20150344636-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device DOW CORNING TORAY CO., LTD. (JP) 2015-12-03 US disclosed
WO-2014104390-A2 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-07-03 WO disclosed
WO-2014104388-A2 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-07-03 WO disclosed