SCHEMBL15848432

SCHEMBL15848432

CCO[SiH](CCc1ccc2ccc3cccc4ccc1c2c34)OCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 6/20 0.40
HPGD P15428 5/20 0.40
HSD17B10 Q99714 4/20 0.40
CYP3A4 P08684 2/20 0.40
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 4/20 0.38
CYP1A2 P05177 4/20 0.34
ERBB2 P04626 1/20 0.34
FYN P06241 1/20 0.34
MAOA P21397 1/20 0.34
ACHE P22303 1/20 0.34
AHR P35869 1/20 0.34
POLB P06746 2/20 0.34
HTT P42858 1/20 0.34
CYP1A1 P04798 1/20 0.33
CYP1B1 Q16678 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15848502 0.84 KMT2A (0.49) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL15848380 0.84 KMT2A (0.42) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL15848165 0.81 HPRT1 (0.41) ALDH1A1HSD17B10TSHRTDP1CYP1A2
SCHEMBL15848457 0.80 CYP1A2 (0.43) KMT2AALDH1A1HSD17B10TDP1KDM4E
SCHEMBL27529936 0.79 KMT2A (0.53) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL8587033 0.77 KMT2A (0.48) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL397619 0.77 KMT2A (0.57) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL15848514 0.76 HTR2A (0.38) MTNR1AHTR2A
SCHEMBL15848602 0.76 KMT2A (0.53) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL719581 0.74 MEN1 (0.63) KMT2AMEN1ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150344735-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device DOW CORNING TORAY CO., LTD. (JP) 2015-12-03 US disclosed
US-20150344636-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device DOW CORNING TORAY CO., LTD. (JP) 2015-12-03 US disclosed
WO-2014104388-A2 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-07-03 WO disclosed
WO-2014104390-A2 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-07-03 WO disclosed