Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927687 | 0.82 | ALDH1A1 (0.62) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL14850480 | 0.82 | ALDH1A1 (0.62) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL15848242 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL4005645 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL29098857 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL10915986 | 0.76 | CHRM3 (0.47) | CYP2C19CHRM2CHRM1CHRM3 | |
| SCHEMBL15848617 | 0.76 | KCNN4 (0.42) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL707651 | 0.72 | MAPT (0.55) | ALDH1A1KMT2ASMN1; SMN2MAPTCYP2C19 | |
| SCHEMBL7057370 | 0.72 | HDAC3 (0.52) | ALDH1A1KMT2AMAPTCYP2C19KCNN4 | |
| SCHEMBL6564357 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150344735-A1 | Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device | DOW CORNING TORAY CO., LTD. (JP) | 2015-12-03 | — | — | US | disclosed |
| WO-2014104388-A2 | CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE | DOW CORNING TORAY CO., LTD. (JP) | 2014-07-03 | — | — | WO | disclosed |