Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10163053 | 0.85 | CYP1A2 (0.42) | PNMTLMNATP53HTTTHRB | |
| SCHEMBL11865637 | 0.83 | PNMT (0.48) | PNMTLMNATP53HTTCSNK2A1 | |
| SCHEMBL17540835 | 0.83 | CSNK2A1 (0.56) | CYP3A4PNMTLMNATP53HTT | |
| SCHEMBL15617289 | 0.83 | PNMT (0.40) | CYP3A4PNMTLMNATP53HTT | |
| SCHEMBL16955282 | 0.83 | THRB (0.47) | PNMTLMNATP53HTTTHRB | |
| Hydrochloric Acid SCHEMBL23833175 | 0.82 | CSNK2A1 (0.57) | PNMTLMNATP53HTTCSNK2A1 | |
| SCHEMBL15424110 | 0.80 | PNMT (0.38) | CYP3A4PNMTLMNATP53HTT | |
| SCHEMBL18996666 | 0.80 | TMEM97 (0.43) | PNMTLMNATP53HTTCSNK2A1 | |
| SCHEMBL27316584 | 0.80 | IDO1 (0.39) | CYP3A4PNMTLMNATP53HTT | |
| SCHEMBL20900793 | 0.78 | CNR2 (0.46) | LMNAHTTTHRBSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9511320-B2 | Polyimide-based macromolecular compound and gas-separation asymmetrical hollow-fibre membrane comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-12-06 | — | — | US | disclosed |
| US-20150217225-A1 | POLYMIDE-BASED MACROMOLECULAR COMPOUND AND GAS-SEPARATION ASYMMETRICAL HOLLOW-FIBRE MEMBRANE COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2015-08-06 | — | — | US | disclosed |
| US-8765781-B2 | Bis-carbazole DNA intercalating agents for antitumor therapy | TRUSTEES OF DARTMOUTH COLLEGE (US) | 2014-07-01 | — | — | US | disclosed |